Rheumatology International

, Volume 32, Issue 10, pp 3315–3317

Drug-induced lupus in anti-TNF-alpha therapy and its treatment with rituximab

  • Juan C. Diaz
  • Santiago Vallejo
  • Carlos A. Cañas
Short Communication


We report three patients with rheumatoid arthritis (RA) who were treated with anti-TNF-α agents and who developed drug-induced lupus (DIL). Two of them received etanercept and the remainder adalimumab. We also present the favorable response observed with the withdrawal of the anti-TNF-alpha agents and the introduction of rituximab. Through this intervention, we observed a very good control of the activity of both DIL and RA without additional adverse reactions.


Rheumatoid arthritis Etanercept Adalimumab Drug-induced lupus Rituximab 


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Juan C. Diaz
    • 1
  • Santiago Vallejo
    • 1
  • Carlos A. Cañas
    • 2
  1. 1.Department of Internal MedicineCES UniversityCaliColombia
  2. 2.Rheumatology UnitFundación Valle del LiliCaliColombia

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