Rheumatology International

, 30:425 | Cite as

Erdheim–Chester disease: a pitfall in DXA measurements

  • Gerhard W. Goerres
  • M. G. Gengenbacher
  • D. Uebelhart
Letter to the editor

Dear Sir,

We would like to report on a 51-year-old female patient with long-standing hypertension who underwent evaluation for possible renovascular disease. A diabetes insipidus was present for the last 30 years, but there were no eye symptoms. Bone involvement was clinically suggested, since the patient previously had symptomatic lytic fractures of two ribs. A symmetrical infiltration of the perirenal fatty tissue and thickening of the wall of the aorta and renal arteries was reported in a computed tomography examination acquired in a different hospital in 2001. Additionally, an involvement of the pericardium and a right atrial tumor was suggested and remained unchanged over years. A final diagnosis of Erdheim–Chester disease (ECD) was based on histological and histochemical evaluation after biopsy of the infiltrates in the perirenal fatty tissue.

The classic triad of ECD is the combination of diabetes insipidus, painless exophthalmos and bone pain [1]. It is a rare non-Langerhans...


Lumbar Spine Alendronate Zoledronic Acid Zoledronic Diabetes Insipidus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Gerhard W. Goerres
    • 1
  • M. G. Gengenbacher
    • 2
  • D. Uebelhart
    • 3
  1. 1.Institut für Medizinische Radiologie, Buergerspital Solothurn/Spital Grenchen soHSolothurnSwitzerland
  2. 2.Bethesda-SpitalBaselSwitzerland
  3. 3.Departement Rheumatologie und Institut für Physikalische Medizin, OsteoporosezentrumUniversitätsSpital ZürichZurichSwitzerland

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