Rheumatology International

, Volume 28, Issue 9, pp 935–937 | Cite as

Henoch–Schonlein purpura with high factor VIII levels and deep venous thrombosis: an association or coincidence?

  • Rezan Topaloglu
  • Umut Selda BayrakciEmail author
  • Barbaros Cil
  • Diclehan Orhon
  • Aysin Bakkaloglu
Case Report


Henoch–Schonlein purpura (HSP) is the most common systemic vasculitis in children. Although long-term outcome is generally good, serious complications may occur. Thrombosis has been reported only as an extremely rare complication of HSP. Here, we describe a 15-year-old-boy with features of HSP, who developed left main iliac, external iliac and femoral vein thrombosis. Factor VIII (FVIII) and homocystein levels were found to be high. This suggests that HSP itself may lead to a prothrombotic state and increase the risk of developing thrombosis in patients who have any risk factors.


Henoch–Schonlein purpura Thrombosis Factor VIII Childhood 


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Rezan Topaloglu
    • 1
  • Umut Selda Bayrakci
    • 1
    • 4
    Email author
  • Barbaros Cil
    • 2
  • Diclehan Orhon
    • 3
  • Aysin Bakkaloglu
    • 1
  1. 1.Department of Pediatric Nephrology and Rheumatology, Faculty of MedicineHacettepe UniversityAnkaraTurkey
  2. 2.Department of Radiology, Faculty of MedicineHacettepe UniversityAnkaraTurkey
  3. 3.Department of Pediatric Pathology, Faculty of MedicineHacettepe UniversityAnkaraTurkey
  4. 4.Pediatrik Nefroloji Unitesi, Tıp FakültesiBaskent UniversitesiBahcelievler, AnkaraTurkiye

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