Rheumatology International

, Volume 26, Issue 9, pp 837–840 | Cite as

Autonomic dysfunction in systemic lupus erythematosus

  • Shalimar
  • Rohini Handa
  • Kishore Kumar Deepak
  • Manvir Bhatia
  • Praveen Aggarwal
  • Ravindra Mohan Pandey
Original Article

Abstract

The objectives were to study the frequency and pattern of autonomic dysfunction in systemic lupus erythematosus (SLE). Fifty-one patients of SLE and 30 age- and sex-matched healthy controls were studied prospectively using a standard battery of noninvasive tests. Autonomic symptoms were seen in 37% patients. On laboratory testing incipient dysfunction was seen in 9 (18%) cases and 1 (3%) control, while atypical involvement was seen in 11 (21%) cases and 6 (20%) controls. Autonomic dysfunction did not correlate with disease duration, lupus activity, disease damage, any particular organ involvement or the presence/absence of peripheral neuropathy. Autonomic neuropathy is not uncommon in lupus and may exist independent of peripheral neuropathy. There are no specific clinical predictors. The clinical significance of autonomic dysfunction detected by laboratory testing warrants longitudinal studies.

Keywords

Systemic lupus erythematosus Autonomic Neuropathy 

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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Shalimar
    • 1
  • Rohini Handa
    • 1
  • Kishore Kumar Deepak
    • 2
  • Manvir Bhatia
    • 3
  • Praveen Aggarwal
    • 1
  • Ravindra Mohan Pandey
    • 4
  1. 1.Department of MedicineAll India Institute of Medical SciencesNew DelhiIndia
  2. 2.Department of PhysiologyAll India Institute of Medical SciencesNew DelhiIndia
  3. 3.Department of NeurologyAll India Institute of Medical SciencesNew DelhiIndia
  4. 4.Department of Bio-statisticsAll India Institute of Medical SciencesNew DelhiIndia

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