Rheumatology International

, Volume 26, Issue 5, pp 465–468 | Cite as

Scleroderma associated with ANCA-associated vasculitis

  • Young Hee Rho
  • Seong Jae Choi
  • Young Ho Lee
  • Jong Dae Ji
  • Gwan Gyu Song
Case Report
First Online:
Received:
Accepted:

Abstract

Scleroderma and ANCA-associated vasculitides (AAV), such as microscopic polyangiitis, are distinct disease entities, but are rarely known to coexist with each other. We have reported on two cases of scleroderma patients for the first time in Korea, and these patients were initially known to have only limited type scleroderma with pulmonary fibrosis, but eventually they were found to be ANCA-positive with the associated clinical features of vasculitis. Both were treated with high-dose steroids and cyclophosphamide and remitted without major sequelae. When scleroderma patients exhibit atypical features such as normotensive renal failure with signs of active inflammation, the possibility of AAV should always be considered.

Keywords

Scleroderma ANCA Vasculitis 
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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Young Hee Rho
    • 1
  • Seong Jae Choi
    • 2
  • Young Ho Lee
    • 2
  • Jong Dae Ji
    • 1
  • Gwan Gyu Song
    • 2
  1. 1.Division of RheumatologyKorea University Anam HospitalSeoulKorea
  2. 2.Division of RheumatologyKorea University Guro HospitalSeoulSouth Korea

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