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Rheumatology International

, Volume 25, Issue 2, pp 130–132 | Cite as

Unusual presentation of lupus nephritis

  • R. GuptaEmail author
  • N. Gulati
  • A. Gupta
  • A. Kumar
  • A. K. Dinda
  • S. K. Sharma
Case Report

Abstract

We report a male patient who presented with pyrexia, generalized lymphadenopathy, hepatosplenomegaly, and pleural effusion with no cutaneous or musculoskeletal symptoms. Despite extensive investigation, no cause was detected. His initial serology was also negative for autoantibodies. The patient was placed on a trial of antitubercular treatment in view of a positive Mantoux test. His disease evolved into the full clinical picture of systemic lupus erythematosus with nephritis (World Health Organisation class IV) and strongly positive antinuclear antibody and dsDNA over a period of months. He was treated successfully with intravenous cyclophosphamide pulses along with oral prednisolone, and the disease was still in remission after 3 years of follow-up.

Keywords

Lymphadenopathy Nephritis Systemic lupus erythematosus 

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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • R. Gupta
    • 1
    Email author
  • N. Gulati
    • 1
  • A. Gupta
    • 1
  • A. Kumar
    • 1
  • A. K. Dinda
    • 2
  • S. K. Sharma
    • 1
  1. 1.Clinical Immunology and Rheumatology Services, Department of MedicineAll India Institute of Medical SciencesNew Delhi India
  2. 2.Department of PathologyAll India Institute of Medical SciencesNew DelhiIndia

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