Rheumatology International

, Volume 25, Issue 2, pp 94–96 | Cite as

Juvenile ankylosing spondylitis—is it the same disease as adult ankylosing spondylitis?

  • Amita AggarwalEmail author
  • Pravin Hissaria
  • Ramnath Misra
Original Article



Juvenile and adult forms of ankylosing spondylitis (AS) have been shown to have different clinical presentation and outcome in Caucasians. We did this retrospective analysis to see if similar differences exist in the Indian population.

Patients and methods

Case records of 210 Indian patients diagnosed with AS according to modified New York criteria were reviewed. Data were collected regarding age of onset, clinical features, drug treatment, and outcome at last follow-up. Patients with onset before 17 years of age were classified as having juvenile AS (JAS) and the rest with adult AS (AAS).


There were 150 patients with AAS and 60 with JAS. The latter had higher male preponderance, more frequent onset with peripheral arthritis, and greater involvement of hip and knee joints. Valvular dysfunction was seen only in patients with JAS.


In this group of subjects, juvenile AS had onset more often with oligoarthritis and enthesitis than with spinal disease. Hip and knee joint involvement was more common in JAS than AAS.


Enthesitis-related arthritis Juvenile idiopathic arthritis Juvenile spondyloarthropathy 


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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • Amita Aggarwal
    • 1
    Email author
  • Pravin Hissaria
    • 1
  • Ramnath Misra
    • 1
  1. 1.Department of ImmunologySanjay Gandhi Postgraduate Institute of Medical SciencesLucknow 226 014India

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