The evolution of peptide mating pheromones in fission yeast
In fungi, sexual reproduction primarily depends on the interaction between peptide pheromones and their receptors. Most ascomycete fungi produce two classes of peptide mating pheromones, a simple peptide and a modified peptide. These peptides are recognized by their corresponding receptors on the surface of cells of the opposite mating type to induce the mating reaction. Pheromone diversification may be associated with reproductive isolation, which restricts gene flow among populations; thus, it remains unclear how pheromones diversify without loss of successful mating. Here, I provide a brief review of recent findings on the ‘asymmetric’ diversification of peptide pheromones in the fission yeast Schizosaccharomyces pombe, and discuss evolution of the mating pheromones in fission yeast.
KeywordsPeptide pheromone Fission yeast G-protein coupled receptor Reproductive isolation Evolution
This work was supported by Grant-in-Aid for JSPS Research Fellow (Grant Number JP15J03416) to T.S., Grant-in-Aid for Young Scientists (B) (Grant Number JP17K15181) to T.S., the Sumitomo Foundation (No. 160924) to T.S., and Dr. Yoshifumi Jigami Memorial Fund, The Society of Yeast Scientists to T.S.
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