Der Pathologe

, Volume 39, Issue 2, pp 107–116 | Cite as

Neues zur WHO-Klassifikation der Knochentumoren

Schwerpunkt: Knorpel, Knochen, Chorda – Molekulare Pathologie
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Zusammenfassung

Die 2013 erschienene 4. Auflage der WHO-Klassifikation der Weichteil- und Knochentumoren baut den seit der 3. Auflage verfolgten Weg weiter aus, Genetik und Pathologie dieser Tumoren zusammen mit Epidemiologie, Klinik und Bildgebung darzustellen. Hinzugekommen sind wenige neue Entitäten, außerdem erfolgten Umbenennungen und Umgruppierungen. Als wichtigster, klinisch relevanter Punkt mit therapeutischen Konsequenzen wurde in Analogie zu den Weichteiltumoren die Einteilung nach dem biologischen Verhalten in 3 Gruppen (gutartig – intermediär – bösartig) auch für die Knochentumoren übernommen.

Schlüsselwörter

Knochentumoren Osteochondromyxom Benigner notochordaler Tumor ISSVA-Klassifikation Atypischer kartilaginärer Tumor Chondromesenchymales Hamartom 

Updates to the WHO classification of bone tumours

Abstract

The fourth edition of the WHO Classification of Soft Tissue and Bone Tumours, published in 2013, extends the approach to describe genetics and pathology of these tumours in the context of epidemiological, clinical and imaging data, which was adopted in the third edition. Added are a few new entities, reclassifications and renamings. The most important point, also of clinical relevance and with consequences for treatment, is the introduction of a stratification of bone tumours based on their biological behaviour into three groups (benign, intermediate, malignant) in analogy to soft tissue tumours.

Keywords

Bone Tumors Osteochondromyxoma Benign notochordal cell tumor ISSVA-classification Atypical cartilaginous tumour Chondromesenchymal hamartoma 

Notes

Danksagung

Herrn Prof. em. Dr. J Adnan Carney, Rochester, USA, danke ich für die Erlaubnis, seine Abbildungen zum Osteochondromyxom aus der WHO-Klassifikation [16] verwenden zu dürfen. Frau Dr. Hiroko Ohgaki, Series Editor der WHO Classification of Tumors, IARC/Frankreich, danke ich für ihre zusätzliche technische Hilfe.

Herrn Prof. Dr. Klaus Wörtler, Institut für Röntgendiagnostik der TU München, danke ich für die Erlaubnis, seine Abbildungen zum BNCT verwenden zu dürfen.

Herrn Dr. Jörg Frege, Berlin, danke ich für die Erlaubnis, den von ihm in der AG Knochentumoren präsentierten Fall 727 eines chondromesenchymalen Hamartoms für diesen Artikel verwenden zu dürfen.

Förderung

Der Autor wird durch die Stiftung Knochentumor-Referenzzentrum Basel unterstützt.

Einhaltung ethischer Richtlinien

Interessenkonflikt

G. Jundt gibt an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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Copyright information

© Springer Medizin Verlag GmbH, ein Teil von Springer Nature 2017

Authors and Affiliations

  1. 1.Knochentumor-Referenzzentrum und DÖSAK-Referenzregister am Institut für PathologieUniversitätsspital BaselBaselSchweiz

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