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Polymer Bulletin

, Volume 76, Issue 2, pp 1023–1039 | Cite as

The study of factors affecting the swelling of ultrasound-prepared hydrogel

  • Rajabali EbrahimiEmail author
Original Paper
First Online:
  • 34 Downloads

Abstract

Gel is a porous continuous 3D network that contains a liquid phase. In most sol–gel systems, the formation of gel is accompanied by the creation of covalent bonds and this formation is irreversible. This study has been done to use a new, fast and bioenvironmental method for synthesis of acrylic hydrogels in the presence of ultrasound and to investigate the effect of different initial conditions of synthesis on swelling and on the structure of the resulting hydrogels. This method does not require any heat and initiator, the reaction is fast, and the gel polymer has a uniform structure with a high swelling capacity. SEM images of samples showed uniform nanostructures with high fine pores. The factors affecting the gel formation were changed during the gel synthesis process to determine its impact on the reaction time and the swelling of the obtained gel. As the power of ultrasound increased, the reaction time shortened and gel swelling and its porosity increased. This happened because of more sonic cavitation and consequently more radical production. The solvent viscosity had similar effects on reaction time and gel swelling. The results of this research can be used in various industries such as pharmaceutics, cosmetics, health, medicine, agriculture and biotechnology in which the swelling properties of superabsorbent hydrogels are used. Also, due to pH-sensitivity and biodegradability, the present hydrogels can be used as a carrier for oral drugs.

Keywords

Hydrogel Ultrasound Synthesis factors Swelling under load Gel content 
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Notes

Compliance with ethical standards

Conflict of interest

The authors declare that there is no conflict of interest regarding the publication of this paper.

Supplementary material

289_2018_2423_MOESM1_ESM.docx (1.1 mb)
Supplementary material 1 (DOCX 1078 kb)

References

  1. 1.
    Vinatoru M, Mason TJ, Calinescu I (2017) Ultrasonically assisted extraction (UAE) and microwave assisted extraction (MAE) of functional compounds from plant materials. Trends Anal Chem 97:159–178CrossRefGoogle Scholar
  2. 2.
    Safarifard V, Morsali A (2015) Applications of ultrasound to the synthesis of nanoscale metal-organic coordination polymers. Coord Chem Rev 292:1–14CrossRefGoogle Scholar
  3. 3.
    Taghizadeh MT, Abdollahi R (2011) Sonolytic, sonocatalytic and sonophotocatalytic degradation of chitosan in the presence of TiO2 nanoparticles. Ultrason Sonochem 18:149–157CrossRefGoogle Scholar
  4. 4.
    Esmaeili BA, Entezari MH, Kafshdare GE (2018) Graphene oxide nanosheets synthesized by ultrasound: experiment versus MD simulation. Appl Sur Sci 451:112–120CrossRefGoogle Scholar
  5. 5.
    Anbarasan R, Jayaseharan J, Sudha M, Gopalan A (2003) Sonochemical polymerization of acrylic acid and acrylamide in the presence of a new redox system. Appl Polym Sci 89:3685–3692CrossRefGoogle Scholar
  6. 6.
    Teo BM, Prescott SW, Ashokkumar M, Grieser F (2008) Ultrasound initiated miniemulsion polymerization of methacrylate monomers. Ultrason Sonochem 15:89–94CrossRefGoogle Scholar
  7. 7.
    Nie M, Wang Q, Qiu G (2008) Enhancement of ultrasonically initiated emulsion polymerization rate using aliphatic alcohols as hydroxyl radical scavengers. Ultrason Sonochem 15:222–226CrossRefGoogle Scholar
  8. 8.
    Cass P, Knower W, Pereeia E, Holmes N, Hughes T (2010) Preparation of hydrogels via ultrasonic polymerization. Ultrason Sonochem 17:326–332CrossRefGoogle Scholar
  9. 9.
    Shirsath R (2013) Removal of brilliant green from wastewater using conventional and ultrasonically prepared poly(acrylic acid) hydrogel loaded with kaolin clay: a comparative study. Ultrason Sonochem 20:914–923CrossRefGoogle Scholar
  10. 10.
    Gh Rezanejade B, Azimi S, Bagheri M (2016) Ultrasonically accelerated synthesis of silver nanocomposite hydrogel based on salep biopolymer: application in Rhodamine dye adsorption. Iran Polym J 25:1047–1063CrossRefGoogle Scholar
  11. 11.
    Wang Y, Xiong Y, Wang J, Zhang X (2017) Ultrasonic assisted fabrication of montmorillonite-lignin hybrid hydrogel: highly efficient swelling behaviors and super-sorbent for dye removal from wastewater. Coll Sur A: Phys Eng Asp 520:903–913CrossRefGoogle Scholar
  12. 12.
    Wang X, Wang Y, He S, Hou H, Hao C (2018) Ultrasonic-assisted synthesis of superabsorbent hydrogels based on sodium lignosulfonate and their adsorption properties for Ni2+. Ultrason Sonochem 40:221–229CrossRefGoogle Scholar
  13. 13.
    Mallakpour S, Abdolmaleki A, Tabesh F (2018) Ultrasonic-assisted manufacturing of new hydrogel nanocomposite biosorbent containing calcium carbonate nanoparticles and tragacanth gum for removal of heavy metal. Ultrason Sonochem 41:572–581CrossRefGoogle Scholar
  14. 14.
    Pruettiphap M, Rempel GL, Pan Q, Kiatkamjornwong S (2017) Morphology and drug release behavior of N-isopropylacrylamide/acrylic acid copolymer as stimuli-responsive nanogels. Iran Polym J 26:957–969CrossRefGoogle Scholar
  15. 15.
    Farshforoush P, Ghanbarzadeh S, Goganian AM, Hamishehkar H (2017) Novel metronidazole-loaded hydrogel as a gastro retentive drug delivery system. Iran Polym J 26:895–901CrossRefGoogle Scholar
  16. 16.
    Abasian M, Hooshangi V, Najafi Moghadam P (2017) Synthesis of polyvinyl alcohol hydrogel grafted by modified Fe3O4 nanoparticles: characterization and doxorubicin delivery studies. Iran Polym J 26:313–322CrossRefGoogle Scholar
  17. 17.
    Sun X-F, Wang H-h, Jing Zh-x, Mohanathas R (2013) Hemicellulose-based pH-sensitive and biodegradable hydrogel for controlled drug delivery. Carbohydr Polym 92:1357–1366CrossRefGoogle Scholar
  18. 18.
    Turan E, Caykara T (2007) Swelling and network parameters of pH-sensitive poly(acrylamide-co-acrylic acid) hydrogels. Appl Polym Sci 106:2000–2007CrossRefGoogle Scholar
  19. 19.
    Sang G, Rezanejade BG, Mirshokraie A, Didehban Kh (2018) A thermo/pH/magnetic-responsive nanogel based on sodium alginate by modifying magnetic graphene oxide: preparation, characterization, and drug delivery. Iran Polym J 27:137–144CrossRefGoogle Scholar
  20. 20.
    Tajima Sh, Tabata Y (2017) Preparation of EpH4 and 3T3L1 cells aggregates incorporating gelatin hydrogel microspheres for a cell condition improvement. Regen Ther 6:90–99CrossRefGoogle Scholar
  21. 21.
    Piątkowski M, Kitala D, Radwan-Pragłowska J, Janus Ł, Klama-Baryła A, Łabuś W, Tomanek E, Glik J, Matýsek D, Kawecki M (2018) Chitosan/amino acid hydrogels with antimicrobial and bioactive properties as new scaffolds for human mesenchymal stem cells culture applicable in wound healing. Express Polym Lett 12:100–112CrossRefGoogle Scholar
  22. 22.
    Kamoun EA, Kenawy ES, Chen X (2017) A review on polymeric hydrogel membranes for wound dressing applications: PVA-based hydrogel dressings. J Adv Res 8:217–233CrossRefGoogle Scholar
  23. 23.
    Deepthi S, Jayakumar R (2017) Alginate nanobeads interspersed fibrin network as in situ forming hydrogel for soft tissue engineering. Bioact Mater.  https://doi.org/10.1016/j.bioactmat.2017.09.005 (in Press) Google Scholar
  24. 24.
    Yu J, Zheng J, Lu Q, Yang Sh, Wang X, Zhang X, Yang W (2016) Reusability and selective adsorption of Pb2+ on chitosan/P(2-acryl amido-2-methyl-1-propanesulfonic acid-co-acrylic acid) hydrogel. ran. Polym J 25:1009–1019Google Scholar
  25. 25.
    Pathak VM, Kumar N (2017) Dataset on the superabsorbent hydrogel synthesis with SiO2 nanoparticle and role in water restoration capability of agriculture soil. Data Brief 13:291–294CrossRefGoogle Scholar
  26. 26.
    Liua Y, Yang F, Feng L, Yang L, Chen L, Wei G, Lu W (2017) In vivo retention of poloxamer-based in situ hydrogels for vaginal application in mouse and rat models. Acta Pharm Sin B 7:502–509CrossRefGoogle Scholar
  27. 27.
    Priyadarshi R, Negi YS (2017) Effect of varying filler concentration on zinc oxide nanoparticle embedded chitosan films as potential food packaging material. J Polym Environ 25:1087–1098CrossRefGoogle Scholar
  28. 28.
    Ehrenhofera A, Elstner M, Wallmersperger Th (2018) Normalization of hydrogel swelling behavior for sensoric and actuatoric applications. Sens Actuators B 255:1343–1353CrossRefGoogle Scholar
  29. 29.
    Nagajothi AJ, Kannan R, Rajashabala S (2017) Studies on electrochemical properties of poly (ethylene oxide)-based gel polymer electrolytes with the effect of chitosan for lithium–sulfur batteries. Polym Bull 74:4887–4897CrossRefGoogle Scholar
  30. 30.
    Thakur VK, Thakur MK, Raghavan P, Kessler MR (2014) Progress in green polymer composites from lignin for multifunctional applications: a review. ACS Sustain Chem Eng 2:1072–1092CrossRefGoogle Scholar
  31. 31.
    Thakur S, Govender PP, Mamo MA, Tamulevicius S, Mishra YK, Thakur VK (2017) Progress in lignin hydrogels and nanocomposites for water purification: future perspectives. Vacuum 146:342–355CrossRefGoogle Scholar
  32. 32.
    Thakur VK, Thakur MK (2014) Recent advances in graft copolymerization and applications of chitosan: a review. ACS Sustain Chem Eng 2:2637–2652CrossRefGoogle Scholar
  33. 33.
    Thakur MK, Thakur VK, Gupta RK, Pappu A (2016) Synthesis and applications of biodegradable soy based graft copolymers: a review. ACS Sustain Chem Eng 4:1–17CrossRefGoogle Scholar
  34. 34.
    Akhtar MF, Hanif M, Ranjha NM (2016) Methods of synthesis of hydrogels: a review. Saudi Pharm J 24:554–559CrossRefGoogle Scholar
  35. 35.
    Treesuppharat W, Rojanapanthu P, Siangsanoh C, Manuspiya H, Ummartyotin S (2017) Synthesis and characterization of bacterial cellulose and gelatin-based hydrogel composites for drug-delivery systems. Biotech Rep 15:84–91CrossRefGoogle Scholar
  36. 36.
    Sun Y, Jiang X, Hou L (2017) A quaternized poly (vinyl alcohol)/chitosan composite alkaline polymer electrolyte: preparation and characterization of the membrane. Iran Polym J 26:531–539CrossRefGoogle Scholar
  37. 37.
    Nesrinne S, Djamel A (2017) Synthesis, characterization and rheological, behavior of pH sensitive poly(acrylamide-co-acrylic acid) hydrogels. Arab J Chem 10:539–547CrossRefGoogle Scholar
  38. 38.
    Isık B, Kıs M (2004) Preparation and determination of swelling behavior of poly(acrylamide-co-acrylic acid) hydrogels in water. Appl Polym Sci 94:1526–1531CrossRefGoogle Scholar
  39. 39.
    Lee M, Wang HS, Song K (2017) Diffusion studies of acrylate hydrogel using raman spectroscopy. Polym (Korea) 41:998–1003CrossRefGoogle Scholar
  40. 40.
    Mohammad N, Atassi Y, Tally M (2017) Synthesis and swelling behavior of metal-chelating superabsorbent hydrogels based on sodium alginate-gpoly(AMPS-co-AA-co-AM) obtained under microwave irradiation. Polym Bull.  https://doi.org/10.1007/s00289-017-1967-5 Google Scholar
  41. 41.
    Yew HC, Misran M (2016) Preparation and characterization of pH dependent κ-carrageenan-chitosan nanoparticle as potential slow release delivery carrier. Iran Polym J 25:1037–1046CrossRefGoogle Scholar
  42. 42.
    Kim DE, Oh HM, Kang SW, Huh KM (2017) Preparation and characterization of acyl glycol chitosan-containing poloxamer gels. Polym (Korea) 41:1033–1040CrossRefGoogle Scholar
  43. 43.
    Choi J (2017) Characterization of hydrogel made by pH-responsive polymer and alginate. Polym (Korea) 41:1046–1051CrossRefGoogle Scholar
  44. 44.
    Hu Y, Chen T, Dong X, Mei Zh (2015) Preparation and characterization of composite hydrogel beads based on sodium alginate. Polym Bull 72:2857–2869CrossRefGoogle Scholar
  45. 45.
    Qi C, An H, Jiang Y, Shi P, Liu Ch, Tan Y (2017) POEGMA hydrogel cross-linked by starch-based microspheres: synthesis and characterization. Iran Polym J 26:323–330CrossRefGoogle Scholar
  46. 46.
    Velders AH, Dijksman JA, Saggiomo V (2017) Hydrogel actuators as responsive instruments for cheap open technology (HARICOT). Appl Mater Today 9:271–275CrossRefGoogle Scholar
  47. 47.
    Ebrahimi R, Salavaty M (2017) Controlled drug delivery of ciprofloxacin from ultrasonic hydrogel. e-Polym 17:1–9CrossRefGoogle Scholar
  48. 48.
    Ebrahimi R, Ebrahimi M (2014) The stimuli-response characters of the hydrogels Prepared from Ultrasound. J Polym Eng 34:625–632Google Scholar

Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Chemistry, College of Science, Takestan BranchIslamic Azad UniversityTakestanIran

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