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Aspergillus galactomannan detection: Trichoderma as a cause of positive results

  • Anthi-Marina Markantonatou
  • Konstantinos Samaras
  • Evangelia Yannaki
  • Evaggelia Zachrou
  • Timoleon-Achilleas Vyzantiadis
Article

Abstract

Aspergillus galactomannan immunoassay is a main diagnostic and monitoring tool in medical mycology. However, the specificity of the method can be skewered by the presence of several other fungi. Trying to diagnose a possible fungal infection of the lower respiratory tract in a haematology patient, it appeared that the fungus Trichoderma longibrachiatum is an additional probable cause of positive galactomannan results. Although, that Trichoderma is a rare but emerging pathogen in immunocompromised patients, the above information could be a caution point in the clinical evaluation of diagnostic results.

Notes

Author Contributions

AMM and KS prepared the solutions, performed several parts of the methodology and searched the references. EZ performed a big part of the technical work of the methodology. EY treated the patient, prepared the clinical data and revised the text. TAV being responsible of the Mycology Lab conceived and designed the study, wrote and revised the paper and performed a part of the methodology.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Anthi-Marina Markantonatou
    • 1
  • Konstantinos Samaras
    • 1
  • Evangelia Yannaki
    • 2
  • Evaggelia Zachrou
    • 1
  • Timoleon-Achilleas Vyzantiadis
    • 1
  1. 1.First Department of Microbiology, Medical SchoolAristotle University of ThessalonikiThessalonikiGreece
  2. 2.Haematology-B.M.T. UnitGeneral Hospital “G. Papanicolaou”ThessalonikiGreece

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