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Psychotherapeut

, Volume 56, Issue 3, pp 216–223 | Cite as

Prädiktoren tumorassoziierter Fatigue

Längsschnittanalyse
  • Susanne KuhntEmail author
  • Carina Ehrensperger
  • Susanne Singer
  • Dirk Hofmeister
  • Kirsten Papsdorf
  • Joachim Weis
  • Rüdiger Zwerenz
  • Elmar Brähler
Originalien

Zusammenfassung

Fatigue wird sehr häufig von Krebspatienten während, aber auch Monate und Jahre nach einer Krebserkrankung und Behandlung beschrieben. Fatigue geht mit starken Beeinträchtigungen im Wohlbefinden und in der Lebensführung der Betroffenen einher. Ziel der vorgestellten Arbeit war es, Faktoren zu identifizieren, die in einem frühen Stadium der Krebsbehandlung die Herausbildung einer Fatigue längere Zeit nach Akutbehandlung vorhersagen helfen. Dazu wurde eine heterogene Gruppe von Tumorpatienten (n=551) im Akutkrankenhaus (t1) und 2 bis 2,5 Jahre danach (t2) zu Fatigue, psychischen, (psycho-)somatischen, soziodemografischen und behandlungsspezifischen Aspekten befragt. Mithilfe von Regressionsanalysen wurde die Fatigue-Belastung während der Akutbehandlung als stärkster Prädiktor für „späte“ tumorassoziierte Fatigue ermittelt. Weitere relevante Faktoren stellen Strahlentherapie und Schmerzen dar. Die Ergebnisse legen nahe, die Diagnostik und Behandlung von akuter Fatigue frühzeitig zu berücksichtigen, um einer möglichen Chronifizierung vorzubeugen. Geeignete diagnostische Instrumente und Behandlungsoptionen werden in übersichtlicher Form vorgestellt.

Schlüsselwörter

Neoplasmen Fatigue Pathologische Bedingungen, Zeichen und Symptome Lebensqualität Prospektive Studien 

Predictors of tumor-associated fatigue

Longitudinal analysis

Abstract

Fatigue is a serious cancer-related syndrome reported by cancer patients during and after treatment. Especially the impact of chronic fatigue on quality of life is substantial. The aim of this study was to identify predictors of fatigue after finishing treatment from an early stage of the cancer treatment. A sample of 551 cancer patients with heterogeneous diagnoses completed questionnaires assessing fatigue, psychological and psychosomatic data plus treatment data. The patients were recruited from an acute care hospital (t1) and the participants completed the questionnaire 2–2.5 years after treatment (t2). Regression analysis showed that the strongest predictor of later fatigue was fatigue during the therapy. Other impact factors are radiotherapy and pain. The results suggest that the diagnosis and treatment of acute fatigue should be carried out at an early stage of cancer treatment to prevent chronic fatigue. Suitable diagnostic methods and treatment options will be presented.

Keywords

Neoplasms Fatigue Pathological conditions, signs and symptoms Quality of life Prospective studies 

Notes

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Susanne Kuhnt
    • 1
    Email author
  • Carina Ehrensperger
    • 1
  • Susanne Singer
    • 1
  • Dirk Hofmeister
    • 1
  • Kirsten Papsdorf
    • 2
  • Joachim Weis
    • 3
  • Rüdiger Zwerenz
    • 4
  • Elmar Brähler
    • 1
  1. 1.Abteilung für Medizinische Psychologie und Medizinische SoziologieUniversität LeipzigLeipzigDeutschland
  2. 2.Klinik und Poliklinik für StrahlentherapieUniversitätsklinikum LeipzigLeipzigDeutschland
  3. 3.Psychosoziale Abteilung, Klinik für TumorbiologieUniversität FreiburgFreiburgDeutschland
  4. 4.Klinik und Poliklinik für Psychosomatische Medizin und PsychotherapieUniversitätsmedizin der Johannes Gutenberg-UniversitätMainzDeutschland

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