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Annals of Hematology

, Volume 80, Issue 3, pp 127–136 | Cite as

Allogeneic transplantation of blood stem cells: Coming of age?

  • Peter Dreger
  • Norbert Schmitz
Review Article

Abstract

Mobilized peripheral blood progenitor cells (PBSC) are increasingly being used instead of bone marrow for allogeneic transplantation. The purpose of the present article is to give a concise and clinically oriented overview on current results and perspectives of allogeneic peripheral blood stem cell transplantation, with particular focus on reconstitution of hematopoiesis and the immune system, graft-versus-host disease, graft-versus-leukemia effects, intensity-reduced conditioning, and graft engineering.

Allogeneic PBSC Graft engineering Cell therapy Minitransplant GVL 

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Copyright information

© Springer-Verlag 2001

Authors and Affiliations

  • Peter Dreger
    • 1
  • Norbert Schmitz
    • 1
  1. 1.Second Department of Medicine, University of Kiel, Chemnitzstrasse 33, 24116 KielGermany

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