Annals of Hematology

, Volume 98, Issue 5, pp 1309–1311 | Cite as

Lymphomatoid granulomatosis mimicking cancer and sarcoidosis

  • Grosse AlexandraEmail author
  • Grosse Claudia
Letter to the Editor


Two cases of misdiagnoses of lymphomatoid granulomatosis are discussed here. Lymphomatoid granulomatosis is an Epstein-Barr virus-associated lymphoproliferative disorder with aggressive behavior. Due to its rarity and many presentations, delay in diagnosis and treatment is common. Its histological features including large atypical B-cells, T cell predominance, angiocentricity, necrosis, and evidence of EBV-positive cells should elicit the diagnosis of lymphomatoid granulomatosis. The settings that are described here have not yet been described in the literature.


Lymphomatoid granulomatosis Epstein-Barr virus Pulmonary nodules Misdiagnosis 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Institute of Pathology and Molecular PathologyUniversity Hospital ZurichZürichSwitzerland

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