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Annals of Hematology

, Volume 94, Issue 11, pp 1923–1924 | Cite as

Deletion of SPRY4 is a frequent event in secondary acute myeloid leukemia

  • Olivia Geiger
  • Stefan Hatzl
  • Karl Kashofer
  • Gerald Hoefler
  • Albert Wölfler
  • Heinz Sill
  • Armin ZebischEmail author
Letter to the Editor

Keywords

Acute Myeloid Leukemia TP53 Mutation Myeloproliferative Neoplasm Pathway Mutation Copy Number Loss 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Funding

This work was supported by the Austrian Science Fund under Grant No. P 26619-B19 (to AZ). Work in the laboratories of AW, HS, and AZ is further supported by Leukämiehilfe Steiermark.

Conflict of Interest

The authors declare that they have no conflict of interest.

Ethical approval and informed consent

This study was approved by the institutional review board of the Medical University of Graz, Austria, and was conducted in accordance with the Declaration of Helsinki. Informed consent was obtained from all individual participants included in this study.

Authors’ contributions

OG and SH carried out the qPCR experiments, analyzed the data, and drafted the manuscript. KK and GH carried out NGS experiments, analyzed the data, and drafted the manuscript. AW and AZ reviewed the clinical data, performed statistical analyses, and drafted the manuscript. HS and AZ designed the study, analyzed the data and drafted the manuscript. All authors read and approved the final typescript.

Supplementary material

277_2015_2445_MOESM1_ESM.doc (141 kb)
ESM 1 (DOC 141 KB)

References

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Olivia Geiger
    • 1
  • Stefan Hatzl
    • 1
  • Karl Kashofer
    • 2
  • Gerald Hoefler
    • 2
  • Albert Wölfler
    • 1
  • Heinz Sill
    • 1
  • Armin Zebisch
    • 1
    Email author
  1. 1.Division of HematologyMedical University of GrazGrazAustria
  2. 2.Institute of PathologyMedical University of GrazGrazAustria

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