Annals of Hematology

, Volume 92, Issue 4, pp 551–552 | Cite as

Neutrophilic myositis sine dermatitis in a neutropenic patient with myelodysplastic syndrome

  • E. Mosnier
  • P. Rousset
  • D. Hugol
  • D. Bouscary
  • E. Aslangul
Letter to the Editor

Dear Editor,

In July 2011, a 66-year-old man was hospitalized for sudden fever (39 °C), severe pain, and edema anterior to the right tibia (Fig.  1). This patient had a history of kappa light chain multiple myeloma, treated by autologous stem cell transplantation, with a relapse beginning in 2009. In 2010, he presented myelodysplastic syndrome complicated by chronic pancytopenia, including profound neutropenia (<0.5 × 10 9/l) for 6 months. Complex results were obtained for cytogenetic analysis: 46, XY, add(8)q(23), del(12),(p11p13) in 14 mitoses; 45, XY, add(8)q(23), del(12),(p11p13) with monosomy 7 in 3 mitoses; 46, XY, der(14) in 2 mitoses; and 46 XY in 1 mitosis. C-reactive protein concentration was initially 200 mg/l. Erysipelas was suspected, and the patient was given amoxicillin for 21 days. He recovered slowly after 1 month. Two weeks after the end of antibiotic treatment, he presented severe pain in the left leg and swelling of the skin covering the tibialis anterior muscle....


Myositis Autologous Stem Cell Transplantation Neutropenic Patient Tibialis Anterior Muscle Erysipelas 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Dr. Elisabeth Aslangul had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. We thank Pr Olivier Chosidow from the Department of Dermatology, Henri Mondor Hospital, Creteil, France, and Pr Claire Le Jeunne, from the Université Paris Descartes, Paris, France, for help during all the stages of the work.

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • E. Mosnier
    • 1
    • 2
  • P. Rousset
    • 2
    • 3
  • D. Hugol
    • 4
  • D. Bouscary
    • 2
    • 5
  • E. Aslangul
    • 1
    • 2
  1. 1.Department of Internal MedicineHôtel DieuParisFrance
  2. 2.Université Paris DescartesParisFrance
  3. 3.Department of RadiologyHôtel DieuParisFrance
  4. 4.Department of PathologyHôtel DieuParisFrance
  5. 5.Department of Clinical HematologyCochinParisFrance

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