To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI).
Materials and Methods
Imaging of eight tracer-filled, stented vessel phantoms and a tracer-filled, non-stented reference phantom for each diameter was performed on a preclinical MPI scanner: eight commercially available coronary stents of different dimensions (diameter: 3–4 mm; length: 11–38 mm) and materials (stainless steel, platinum–chromium) were implanted into silicone vessel phantoms. For comparison, all vessel phantoms were also visualized by MRI and CT. Two radiologists assessed the images regarding stent-induced artifacts using a 5-point grading scale.
The visualization of all stented vessel phantoms was achieved without stent-induced artifacts with MPI. In contrast, MRI and CT images revealed multiform stent-induced artifacts.
Given its clinical introduction, MPI has the potential to overcome the disadvantages of MRI and CT concerning the visualization of the stent lumen.
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The authors would like to thank Ankit Malhotra (Institute of Medical Engineering, University of Lübeck, Lübeck, Germany) for assisting with the phantoms and Armin Herzog (Department of Radiology and Nuclear Medicine, University Hospital Schleswig–Holstein, Campus Lübeck, Germany) for technical support regarding the CT image acquisition.
This study partially was funded by Federal Ministry of Education and Research BMBF Grant Nos. 13GW0071D, 13GW0069A, 13GW0230B, and 01DL17010A.
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The authors declare that they have no conflict of interest.
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Wegner, F., Friedrich, T., von Gladiss, A. et al. Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study. Cardiovasc Intervent Radiol 43, 331–338 (2020). https://doi.org/10.1007/s00270-019-02347-x
- Magnetic particle imaging
- Magnetic resonance imaging
- Computed tomography