Application of Percutaneous Osteoplasty in Treating Pelvic Bone Metastases: Efficacy and Safety
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Percutaneous vertebroplasty has been a good option to treat vertebral metastases. The pelvic bone is a common site of spread for many cancers. Using follow-up data for 126 patients, we evaluated the safety and efficacy of percutaneous osteoplasty (POP) to treat pelvic bone metastases.
Materials and Methods
In this retrospective study, 126 patients (mean age 57.45 ± 11.46 years old) with 178 lesions were treated using POP. The visual analog scale (VAS), Oswestry Disability Index (ODI), and the changes in the patient’s use of painkillers were used to evaluate pain and quality of life before the procedure, and at 3 days and 1, 3, 6, 9, and 12 months after the procedure.
Technical success was achieved in all patients. The mean VAS scores decreased significantly from 6.87 ± 1.33 before the procedure to 3.33 ± 1.94 by day 3 after the procedure (P < 0.05), 2.26 ± 1.59 at 1 month (P < 0.05), 1.89 ± 1.53 at 3 months (P < 0.05), 1.87 ± 1.46 at 6 months (P < 0.05), 1.90 ± 1.47 at 9 months (P < 0.05), and 1.49 ± 1.17 at 12 months (P < 0.05). The ODI also changed after the procedure, with significant differences between baseline scores and at each follow-up examination (P < 0.05). Pain relief was achieved in 118 patients (93.65%); however, pain relief was not obvious in seven patients (5.56%), and pain was aggravated in one patient (0.79%). Extraosseous cement leakage occurred in 35 patients (27.78%) without causing any clinical complications.
Percutaneous osteoplasty is a safe and effective choice for patients with painful osteolytic pelvic bone metastases. It can relieve pain, reduce disability, and improve function.
Level of Evidence
Level 3b, retrospective study.
KeywordsPelvic bone metastases Percutaneous osteoplasty POP Interventional therapy
This work was sponsored by grant Natural Fund from Shanghai Science and Technology Commission (Grant numbers 18ZR1429400, 19411971800), China.
Compliance with Ethical Standards
Conflict of interest
The authors declare that they have no conflict of interest.
Human and Animal Rights
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
- 3.Tian QH, He CJ, Wu CG, et al. Comparison of percutaneous cementoplasty with and without interventional internal fixation for impending malignant pathological fracture of the proximal femur. Cardiovasc Interv Radiol. 2016;39(1):81–9.Google Scholar
- 4.Sun G, Jin P, Li M, et al. Percutaneous cementoplasty for painful osteolytic humeral metastases: initial experience with an innovative technique. Skelet Radiol. 2011;40(10):1345–8.Google Scholar
- 9.Clarencon F, Jean B, Pham HP, et al. Value of percutaneous radiofrequency ablation with or without percutaneous vertebroplasty for pain relief and functional recovery in painful bone metastases. Skelet Radiol. 2013;42(1):25–36.Google Scholar
- 11.Laitinen MK, Parry MC, Albergo JI, et al. Is computer navigation when used in the surgery of iliosacral pelvic bone tumours safer for the patient? Bone Jt J. 2017;99-B(2):261–6.Google Scholar
- 17.Trumm CG, Pahl A, Helmberger TK, et al. CT fluoroscopy-guided percutaneous vertebroplasty in spinal malignancy: technical results, PMMA leakages, and complications in 202 patients. Skelet Radiol. 2012;41(11):1391–400.Google Scholar
- 21.Wei Z, Hui W, Ji-Hong H, et al. Palliative pain relief and safety of percutaneous radiofrequency ablation combined with cement injection for bone metastasis. Jpn J Clin Oncol. 2018;48(8):753–9.Google Scholar
- 23.Kang HG, Roh YW, Kim HS. The treatment of metastasis to the femoral neck using percutaneous hollow perforated screws with cement augmentation. J Bone Jt Surg Br. 2009;91(8):1078–82.Google Scholar
- 28.Burgard CA, Dinkel J, Strobl F, et al. CT fluoroscopy-guided percutaneous osteoplasty with or without radiofrequency ablation in the treatment of painful extraspinal and spinal bone metastases: technical outcome and complications in 29 patients. Diagn Interv Radiol. 2018;24:158–65.PubMedPubMedCentralGoogle Scholar
- 29.Lee JH, Kim SY, Ok HG, et al. Extraspinal percutaneous osteoplasty for the treatment of painful bony metastasis. J Kor Med Sci. 2018;33:61.Google Scholar
- 30.Wallace AN, Huang AJ, Vaswani D, et al. Combination acetabular radiofrequency ablation and cementoplasty using a navigational radiofrequency ablation device and ultrahigh viscosity cement: technical note. Skelet Radiol. 2016;45(3):401–5.Google Scholar