CardioVascular and Interventional Radiology

, Volume 42, Issue 3, pp 381–388 | Cite as

Endovascular Treatment of Arterial Complications After Liver Transplantation: Long-Term Follow-Up Evaluated on Doppler Ultrasound and Magnetic Resonance Cholangiopancreatography

  • Romain BreguetEmail author
  • Federica Dondero
  • Lawrence Pupulim
  • Nicolas Goossens
  • Ailton Sepulveda
  • Claire Francoz
  • François Durand
  • Sylvain Terraz
  • Valérie Vilgrain
  • Maxime Ronot
Clinical Investigation Arterial Interventions
Part of the following topical collections:
  1. Arterial Interventions



To evaluate long-term arterial patency and abnormalities of bile ducts in patients that had endovascular treatment for arterial complications after liver transplantation (LT).

Materials and Methods

Between 2004 and 2014, 1048 LTs were consecutively performed in our institution and 53 patients (42 men; age range 19–69) were diagnosed and treated by endovascular techniques for arterial complications such as stenosis, thrombosis, dissection or kinking of the hepatic artery (HA). Radiological and surgical data were retrospectively analyzed, and survivors were contacted to undergo follow-up Doppler ultrasound (DUS) of the HA and magnetic resonance cholangiopancreatography.


The primary technical success of endovascular treatment was 94% (n = 50). The patency rate of HA at 5-year was 81%. After a median follow-up of 58 months, 17 patients (32%) developed radiological features of ischemic cholangiopathy (IC), including 7 patients with abnormal DUS and 10 with normal DUS. Patients who presented with complications of the HA in the first 3 months after LT developed IC more frequently (42%) than others (12%) (p = 0.028). No other factor was associated with the development of IC.


IC was more often observed when HA complication occurred within the first 3 months after LT. The presence of IC was not excluded by a normal DUS during follow-up.


Liver transplantation Hepatic artery Endovascular procedures Ischemic cholangiopathy 



Catheter-directed thrombolysis


Confidence interval


Doppler ultrasound


Hepatic artery


Ischemic cholangiopathy


Multidetector-computed tomography/arteriography


Magnetic resonance cholangiopancreatography


Liver transplantation


Percutaneous transluminal angioplasty


Picture archiving and communication system


Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Standards

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2018

Authors and Affiliations

  • Romain Breguet
    • 1
    • 2
    Email author
  • Federica Dondero
    • 3
  • Lawrence Pupulim
    • 1
    • 2
  • Nicolas Goossens
    • 4
  • Ailton Sepulveda
    • 3
  • Claire Francoz
    • 5
    • 6
  • François Durand
    • 5
    • 6
  • Sylvain Terraz
    • 1
    • 2
  • Valérie Vilgrain
    • 5
    • 6
  • Maxime Ronot
    • 5
    • 6
  1. 1.Department of RadiologyUniversity Hospitals of GenevaGeneva 14Switzerland
  2. 2.Hepato-Pancreato-Biliary CentreUniversity Hospitals of GenevaGenevaSwitzerland
  3. 3.Department of Hepatobiliopancreatic Surgery, Hôpital Beaujon, UNITY Hospitalo-Universitary DepartmentHôpitaux Paris Nord Val de Seine (AP-HP)ClichyFrance
  4. 4.Department of Gastroenterology and HepatologyUniversity Hospitals of GenevaGenevaSwitzerland
  5. 5.Department of Hepatology, Hôpital BeaujonHôpitaux Paris Nord Val de Seine (AP-HP)ClichyFrance
  6. 6.Sorbonne Paris Cité, CRI, U1149Paris Diderot UniversityParisFrance

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