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CardioVascular and Interventional Radiology

, Volume 42, Issue 1, pp 110–115 | Cite as

Endovascular Stroke Therapy with a Novel 6-French Aspiration Catheter

  • M. Bretzner
  • L. Estrade
  • M. Ferrigno
  • F. Bala
  • F. Boustia
  • A. Kazemi
  • J. P. Pruvo
  • H. Henon
  • N. BricoutEmail author
Clinical Investigation Stroke/Neurointerventions
Part of the following topical collections:
  1. Stroke/Neurointerventions

Abstract

Background and Purpose

Direct thrombus aspiration is increasingly used as a first-line therapy in acute ischemic stroke with large vessel occlusion. We assessed the performance and safety of a novel aspiration catheter available: the 6-French AXS Catalyst catheter.

Materials and Methods

We conducted a cohort study from a prospective clinical registry of consecutive stroke patients treated by mechanical thrombectomy between March 2016 and July 2016. Baseline clinical and imaging characteristics, recanalization rates, complications, and clinical outcomes were analyzed.

Results

Among the 60 patients included, 30 were treated using aspiration alone, 14 were treated using aspiration and then stent retriever as a rescue therapy, and 16 were treated using aspiration combined with a stent retriever straightaway. Successful recanalization (mTICI2b/3) was achieved in 85% patients and functional independence in 48.3%. We observed one intracranial perforation and one vertebral artery dissection. Symptomatic intracranial hemorrhage occurred in 5% and mortality in 21.7%.

Conclusion

Endovascular stroke therapy using the AXS Catalyst catheter seems safe and effective, with similar performance than other reperfusion catheters.

Keywords

Stroke Thrombectomy Catheter 

Abbreviations

AIS

Acute ischemic stroke

ADAPT

A Direct Aspiration First Pass Technique

HI

Hemorrhagic infarction

ICA

Internal carotid artery

IVT

Intravenous thrombolysis

LVO

Large vessel occlusion

MCA

Middle cerebral artery

MT

Mechanical thrombectomy

mTICI

Modified Thrombolysis In Cerebral Infarction

PH

Parenchymal hemorrhage

sICH

Symptomatic intracerebral hemorrhage

Notes

Funding

This work was supported by Stryker Neurovascular. The funding source was not involved in study design, monitoring, data collection, statistical analyses, interpretation of results, or manuscript writing.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Consent for Publication

Consent for publication was obtained for every individual person’s data included in the study.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2018

Authors and Affiliations

  1. 1.Department of Interventional NeuroradiologyUniversity of LilleLilleFrance
  2. 2.Department of NeurologyUniversity of LilleLilleFrance
  3. 3.Department of Interventional NeuroradiologyUniversity of ToursToursFrance
  4. 4.INSERM U1171 - Degenerative and Vascular Cognitive DisordersLilleFrance

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