CardioVascular and Interventional Radiology

, Volume 39, Issue 8, pp 1165–1169 | Cite as

Intra-arterial Ultra-low-Dose CT Angiography of Lower Extremity in Diabetic Patients

  • Ali Özgen
  • Soner Sanioğlu
  • Uğur Anıl Bingöl
Technical Note



To image lower extremity arteries by CT angiography using a very low-dose intra-arterial contrast medium in patients with high risk of developing contrast-induced nephropathy (CIN).

Materials and Methods

Three cases with long-standing diabetes mellitus and signs of lower extremity atherosclerotic disease were evaluated by CT angiography using 0.1 ml/kg of the body weight of contrast medium given via 10-cm-long 4F introducer by puncturing the CFA. Images were evaluated by an interventional radiologist and a cardiovascular surgeon. Density values of the lower extremity arteries were also calculated. Findings in two cases were compared with digital subtraction angiography images performed for percutaneous revascularization. Blood creatinine levels were followed for possible CIN.


Intra-arterial CT angiography images were considered diagnostic in all patients and optimal in one patient. No patient developed CIN after intra-arterial CT angiography, while one patient developed CIN after percutaneous intervention.


Intra-arterial CT angiography of lower extremity might be performed in selected patients with high risk of developing CIN. Our limited experience suggests that as low as of 0.1 ml/kg of the body weight of contrast medium may result in adequate diagnostic imaging.


Limb ischemia Endovascular Femoropopliteal Peripheral artery disease Contrast agents Diabetes mellitus CT/CTA 


Compliance with Ethical Standards

Conflict of interest

There is no conflict of interest or any financial support.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2016

Authors and Affiliations

  • Ali Özgen
    • 1
  • Soner Sanioğlu
    • 2
  • Uğur Anıl Bingöl
    • 3
  1. 1.Department of RadiologyYeditepe University HospitalAtaşehirTurkey
  2. 2.Department of Cardiovascular SurgeryYeditepe University HospitalAtaşehirTurkey
  3. 3.Department of Plastic SurgeryYeditepe University HospitalAtaşehirTurkey

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