Clinical Results After Prostatic Artery Embolization Using the PErFecTED Technique: A Single-Center Study
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Prostatic artery embolization (PAE) has been performed for a few years, but there is no report on PAE using the PErFecTED technique outside from the team that initiated this approach.
This single-center retrospective open label study reports our experience and clinical results on patients suffering from symptomatic BPH, who underwent PAE aiming at using the PErFecTED technique.
Materials and Methods
We treated 32 consecutive patients, mean age 65 (52–84 years old) between December 2013 and January 2015. Patients were referred for PAE after failure of medical treatment and refusal or contra-indication to surgery. They were treated using the PErFecTED technique, when feasible, with 300–500 µm calibrated microspheres (two-night hospital stay or outpatient procedure). Follow-up was performed at 3, 6, and 12 months.
We had a 100 % immediate technical success of embolization (68 % of feasibility of the PErFecTED technique) with no immediate complications. After a mean follow-up of 7.7 months, we observed a 78 % rate of clinical success. Mean IPSS decreased from 15.3 to 4.2 (p = .03), mean QoL from 5.4 to 2 (p = .03), mean Qmax increased from 9.2 to 19.2 (p = .25), mean prostatic volume decreased from 91 to 62 (p = .009) mL. There was no retrograde ejaculation and no major complication.
PAE using the PErFecTED technique is a safe and efficient technique to treat bothersome LUTS related to BPH. It is of interest to note that the PErFecTED technique cannot be performed in some cases for anatomical reasons.
KeywordsBenign Prostatic Hyperplasia Lower Urinary Tract Symptom Clinical Success International Prostatic Symptom Score Acute Urinary Retention
Prostatic artery embolization
Benign prostate hyperplasia
Lower urinary track symptoms
International prostatic symptoms score
International index of erectile function
Quality of life
Maximum urinary flow
total Prostate serum antigen
Cone-beam computed tomography
Compliance with Ethical Standards
Conflict of Interest
Gregory Amouyal, Nicolas Thiounn, Olivier Pellerin, Lin Yen-Ting, Costantino Del Giudice, Carole Dean, Helena Pereira, and Gilles Chatellier have nothing to disclose; Marc Sapoval has financial support from Merit Medical (Salt lake city, USA) for attending/speaking at symposia/congresses and for educational programs.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in this study.
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