CardioVascular and Interventional Radiology

, Volume 38, Issue 4, pp 1031–1035 | Cite as

Percutaneous Irreversible Electroporation of a Large Centrally Located Hepatocellular Adenoma in a Woman with a Pregnancy Wish

  • Hester J. Scheffer
  • Marleen C. A. M. Melenhorst
  • Aukje A. J. M. van Tilborg
  • Karin Nielsen
  • Karin M. van Nieuwkerk
  • Richard A. de Vries
  • Petrousjka (M.P.) van den Tol
  • Martijn R. Meijerink
Case Report


Irreversible electroporation (IRE) is a novel image-guided ablation technique that is rapidly gaining popularity in the treatment of malignant liver tumors located near large vessels or bile ducts. We describe a 28-year-old female patient with a 5 cm large, centrally located hepatocellular adenoma who wished to get pregnant. Regarding the risk of growth and rupture of the adenoma caused by hormonal changes during pregnancy, treatment of the tumor was advised prior to pregnancy. However, due to its central location, the tumor was considered unsuitable for resection and thermal ablation. Percutaneous CT-guided IRE was performed without complications and led to rapid and impressive tumor shrinkage. Subsequent pregnancy and delivery went uncomplicated. This case report suggests that the indication for IRE may extend to the treatment of benign liver tumors that cannot be treated safely otherwise.


Irreversible electroporation (IRE) Electroporation/methods Hepatocellular adenoma/HCA Pregnancy Tumor ablation/percutaneous Ablation techniques/adverse effects 


Conflict of interest

Hester J Scheffer, Marleen CAM Melenhorst, Aukje AJM van Tilborg, Karin Nielsen, Karin M van Nieuwkerk, Richard A de Vries, Petrousjka (MP) van den Tol and Martijn R Meijerink have no conflicts of interest to declare.

Informed Consent

Informed consent was provided by the patient.


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Copyright information

© Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2014

Authors and Affiliations

  • Hester J. Scheffer
    • 1
  • Marleen C. A. M. Melenhorst
    • 1
  • Aukje A. J. M. van Tilborg
    • 1
  • Karin Nielsen
    • 2
  • Karin M. van Nieuwkerk
    • 3
  • Richard A. de Vries
    • 3
  • Petrousjka (M.P.) van den Tol
    • 2
  • Martijn R. Meijerink
    • 1
  1. 1.Department of Radiology and Nuclear MedicineVU University Medical CenterAmsterdamThe Netherlands
  2. 2.Department of SurgeryAmsterdamThe Netherlands
  3. 3.Department of Gastroenterology and HepatologyVU University Medical CenterAmsterdamThe Netherlands

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