CardioVascular and Interventional Radiology

, Volume 37, Issue 3, pp 815–818 | Cite as

Regions of High Wall Stress Can Predict the Future Location of Rupture of Abdominal Aortic Aneurysm

  • Barry J. Doyle
  • Timothy M. McGloughlin
  • Karol Miller
  • Janet T. Powell
  • Paul E. Norman
Case Report


Predicting the wall stress in abdominal aortic aneurysm (AAA) using computational modeling may be a useful adjunct to traditional clinical parameters that indicate the risk of rupture. Maximum diameter has been shown to have many limitations, and using current technology it is possible to provide a patient-specific computational risk assessment using routinely acquired medical images. We present a case of AAA rupture where the exact rupture point was clearly visible on the computed tomography (CT) images. A blind computational study based on CT scans acquired 4 months earlier predicted elevated wall stresses in the same region that later experienced rupture.


Abdominal aortic aneurysm Computational model Wall stress Rupture Risk 



This work was funded by The University of Western Australia Research Fellowship and the UWA ECM Research Development Award. The authors are grateful for assistance from staff in the Imaging Department of Fremantle Hospital.

Conflict of interest

Barry Doyle, Timothy McGloughlin, Karol Miller, Janet Powell, and Paul Norman have no conflict of interest to declare.


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Copyright information

© Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2014

Authors and Affiliations

  • Barry J. Doyle
    • 1
    • 2
  • Timothy M. McGloughlin
    • 3
  • Karol Miller
    • 1
    • 4
  • Janet T. Powell
    • 5
  • Paul E. Norman
    • 6
  1. 1.Intelligent Systems for Medicine Laboratory, School of Mechanical and Chemical EngineeringThe University of Western AustraliaPerthAustralia
  2. 2.Centre for Cardiovascular ScienceThe University of EdinburghEdinburghUK
  3. 3.Department of Mechanical, Aeronautical and Biomedical Engineering, Centre for Applied Biomedical Engineering Research, and the Materials and Surface Science InstituteUniversity of LimerickLimerickIreland
  4. 4.Institute of Mechanics and Advanced Materials, School of EngineeringCardiff UniversityCardiffUK
  5. 5.Vascular Surgery Research GroupImperial CollegeLondonUK
  6. 6.School of Surgery, Fremantle HospitalThe University of Western AustraliaFremantleAustralia

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