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CardioVascular and Interventional Radiology

, Volume 36, Issue 4, pp 978–986 | Cite as

Clinical, Laboratorial, and Urodynamic Findings of Prostatic Artery Embolization for the Treatment of Urinary Retention Related to Benign Prostatic Hyperplasia. A Prospective Single-Center Pilot Study

  • Alberto A. Antunes
  • Francisco C. CarnevaleEmail author
  • Joaquim M. da Motta Leal Filho
  • Eduardo M. Yoshinaga
  • Luciana M. O. Cerri
  • Ronaldo H. Baroni
  • Antonio S. Z. Marcelino
  • Giovanni G. Cerri
  • Miguel Srougi
Clinical Investigation

Abstract

Purpose

This study was designed to describe the clinical, laboratorial, and urodynamic findings of prostatic artery embolization (PAE) in patients with urinary retention due to benign prostatic hyperplasia (BPH).

Methods

A prospective study of 11 patients with urinary retention due to BPH was conducted. Patients underwent physical examination, prostate specific antigen (PSA) measurement, transrectal ultrasound, and magnetic resonance imaging. International prostate symptom score (IPSS), quality of life (QoL), and urodynamic testing were used to assess the outcome before and after 1 year.

Results

Clinical success was 91 % (10/11 patients) with a mean follow-up of 22.3 months (range, 12–41 months). At the first year follow-up, the mean IPSS score was 2.8 points (p = 0.04), mean QoL was 0.4 points (p = 0.001), mean PSA decreased from 10.1 to 4.3 ng/mL (p = 0.003), maximum urinary flow (Qmax) improved from 4.2 to 10.8 mL/sec (p = 0.009), and detrusor pressure (Pdet) decreased from 85.7 to 51.5 cm H2O (p = 0.007). Before PAE, Bladder Outlet Obstruction Index (BOOI) showed values >40 in 100 % of patients. After PAE, 30 % of patients were >40 (obstructed), 40 % were between 20 and 40 (undetermined), and 30 % were <20 (unobstructed). Patients with a BOOI <20 had higher PSA values at 1-day after PAE.

Conclusions

Clinical and urodynamic parameters improved significantly after PAE in patients with acute urinary retention due to BPH. Total PSA at day 1 after PAE was higher in patients with unobstructed values in pressure flow studies.

Keywords

Clinical practice Imaging Arterial intervention Embolization/embolisation/ embolotherapy Endovascular treatment Transcatheter therapy MRI/ MRA Prostate Urinary tract 

Notes

Conflict of interest

Alberto Azoubel Antunes, Francisco Cesar Carnevale, Joaquim Mauricio da Motta-Leal-Filho, Eduardo Muracca Yoshinaga, Luciana Mendes de Oliveira Cerri, Ronaldo Hueb Baroni, Antonio Sergio Zafred Marcelino, Giovanni Guido Cerri, Miguel Srougi have no conflict of interest.

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Copyright information

© Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2013

Authors and Affiliations

  • Alberto A. Antunes
    • 1
    • 6
  • Francisco C. Carnevale
    • 2
    Email author
  • Joaquim M. da Motta Leal Filho
    • 2
  • Eduardo M. Yoshinaga
    • 1
  • Luciana M. O. Cerri
    • 3
  • Ronaldo H. Baroni
    • 4
  • Antonio S. Z. Marcelino
    • 3
  • Giovanni G. Cerri
    • 5
  • Miguel Srougi
    • 1
  1. 1.Division of UrologyUniversity of Sao Paulo Medical SchoolSão PauloBrazil
  2. 2.Interventional Radiology UnitUniversity of Sao Paulo Medical SchoolSão PauloBrazil
  3. 3.Ultrasound UnitUniversity of Sao Paulo Medical SchoolSão PauloBrazil
  4. 4.Magnetic Resonance UnitUniversity of Sao Paulo Medical SchoolSão PauloBrazil
  5. 5.Radiology DepartmentUniversity of Sao Paulo Medical SchoolSão PauloBrazil
  6. 6.São PauloBrazil

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