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CardioVascular and Interventional Radiology

, Volume 36, Issue 4, pp 1144–1146 | Cite as

Hyaluronic Acid Gel Injection to Prevent Thermal Injury of Adjacent Gastrointestinal Tract during Percutaneous Liver Radiofrequency Ablation

  • Takaaki HasegawaEmail author
  • Haruyuki Takaki
  • Hideki Miyagi
  • Atsuhiro Nakatsuka
  • Junji Uraki
  • Takashi Yamanaka
  • Masashi Fujimori
  • Hajime Sakuma
  • Koichiro Yamakado
Technical Note

Abstract

This study evaluated the safety, feasibility, and clinical utility of hyaluronic acid gel injection to separate the gastrointestinal tract from the tumor during liver radiofrequency ablation (RFA). Eleven patients with liver tumors measuring 0.9–3.5 cm (mean ± standard deviation, 2.1 ± 0.8 cm) that were adjacent to the gastrointestinal tracts received RFA after the mixture of hyaluronic acid gel and contrast material (volume, 26.4 ± 14.5 mL; range, 10–60 mL) was injected between the tumor and the gastrointestinal tract under computed tomographic–fluoroscopic guidance. Each tumor was separated from the gastrointestinal tract by 1.0–1.5 cm (distance, 1.2 ± 0.2 cm) after injection of hyaluronic acid gel, and subsequent RFA was performed without any complications in all patients. Although tumor enhancement disappeared in all patients, local tumor progression was found in a patient (9.1 %, 1 of 11) during the follow-up of 5.5 ± 3.2 months (range, 0.4–9.9 months). In conclusion, hyaluronic acid gel injection is a safe and useful technique to avoid thermal injury of the adjacent gastrointestinal tract during liver RFA.

Keywords

Hyaluronic acid Liver Radiofrequency ablation Thermal injury 

Notes

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media New York and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2013

Authors and Affiliations

  • Takaaki Hasegawa
    • 1
    Email author
  • Haruyuki Takaki
    • 1
  • Hideki Miyagi
    • 1
  • Atsuhiro Nakatsuka
    • 1
  • Junji Uraki
    • 1
  • Takashi Yamanaka
    • 1
  • Masashi Fujimori
    • 1
  • Hajime Sakuma
    • 1
  • Koichiro Yamakado
    • 1
  1. 1.Department of RadiologyMie University School of MedicineTsuJapan

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