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CardioVascular and Interventional Radiology

, Volume 36, Issue 1, pp 245–248 | Cite as

Novel Percutaneous Radiofrequency Ablation of Portal Vein Tumor Thrombus: Safety and Feasibility

  • Malkhaz Mizandari
  • Guokun Ao
  • Yaojun Zhang
  • Xi Feng
  • Qiang Shen
  • Minshan Chen
  • WanYee Lau
  • Joanna Nicholls
  • Long Jiao
  • Nagy HabibEmail author
Technical Note

Abstract

Purpose

We report our experience of the safety of partial recanalization of the portal vein using a novel endovascular radiofrequency (RF) catheter for portal vein tumor thrombosis.

Methods

Six patients with liver cancer and tumor thrombus in the portal vein underwent percutaneous intravascular radiofrequency ablation (RFA) using an endovascular bipolar RF device. A 0.035-inch guidewire was introduced into a tributary of the portal vein and through which a 5G guide catheter was introduced into the main portal vein. After manipulation of the guide catheter over the thrombus under digital subtraction angiography, the endovascular RF device was inserted and activated around the thrombus.

Results

There were no observed technique specific complications, such as hemorrhage, vessel perforation, or infection. Post-RFA portography showed partial recanalization of portal vein.

Conclusions

RFA of portal vein tumor thrombus in patients with hepatocellular carcinoma is technically feasible and warrants further investigation to assess efficacy compared with current recanalization techniques.

Keywords

Endovascular radiofrequency ablation Catheter Portal vein thrombus 

Notes

Conflict of interest

Joanna Nicholls and Nagy Habib are shareholders and directors of EMcision Limited, the company that developed the Habib™ VesOpen device. None of the other authors have a conflict of interest or a financial disclosure to declare.

Supplementary material

Supplementary Video. A video of percutaneous endovascular radiofrequency ablation of tumor thrombosis in right and main branch portal vein (MPEG 2928 kb)

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Copyright information

© Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2012

Authors and Affiliations

  • Malkhaz Mizandari
    • 1
  • Guokun Ao
    • 2
  • Yaojun Zhang
    • 3
  • Xi Feng
    • 3
  • Qiang Shen
    • 4
  • Minshan Chen
    • 5
  • WanYee Lau
    • 6
  • Joanna Nicholls
    • 3
    • 7
  • Long Jiao
    • 3
  • Nagy Habib
    • 3
    • 7
    Email author
  1. 1.High Technology Medical Center, Tbilisi State Medical UniversityTbilisiGeorgia
  2. 2.Department on OncologyThe 309 Hospital of People’s Liberation ArmyHaiDian District, BeijingChina
  3. 3.Department of Surgery and CancerImperial College LondonLondonUK
  4. 4.The First Minimally Invasive Department of Eastern Hepatobiliary Surgery HospitalShanghaiChina
  5. 5.Department of Hepatobiliary SurgeryCancer Centre of Sun Yat-Sen UniversityGuangzhouChina
  6. 6.Department of Surgery, Faculty of MedicineThe Chinese University of Hong KongHong KongChina
  7. 7.Department of Surgery, EMcision LimitedHammersmith HospitalLondonUK

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