CardioVascular and Interventional Radiology

, Volume 36, Issue 2, pp 545–548 | Cite as

Intra-arterial Autologous Bone Marrow Cell Transplantation in a Patient with Upper-extremity Critical Limb Ischemia

  • Juraj Madaric
  • Andrej Klepanec
  • Martin Mistrik
  • Cestmir Altaner
  • Ivan Vulev
Case Report


Induction of therapeutic angiogenesis by autologous bone marrow mononuclear cell transplantation has been identified as a potential new option in patients with advanced lower-limb ischemia. There is little evidence of the benefit of intra-arterial cell application in upper-limb critical ischemia. We describe a patient with upper-extremity critical limb ischemia with digital gangrene resulting from hypothenar hammer syndrome successfully treated by intra-arterial autologous bone marrow mononuclear cell transplantation.


Critical limb ischemia Hypothenar hammer syndrome Intra-arterial administration Therapeutic angiogenesis Upper extremity 


Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2012

Authors and Affiliations

  • Juraj Madaric
    • 1
  • Andrej Klepanec
    • 2
  • Martin Mistrik
    • 3
  • Cestmir Altaner
    • 4
  • Ivan Vulev
    • 2
  1. 1.Department of Cardiology and AngiologyNational Institute of Cardiovascular Diseases (NUSCH) and Slovak Medical UniversityBratislavaSlovakia
  2. 2.Department of Diagnostic and Interventional RadiologyNational Institute of Cardiovascular DiseasesBratislavaSlovakia
  3. 3.Clinic of Hematology and Transfusiology, Faculty HospitalBratislavaSlovakia
  4. 4.Institute of Experimental OncologySlovak Academy of ScienceBratislavaSlovakia

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