CardioVascular and Interventional Radiology

, Volume 36, Issue 1, pp 276–279 | Cite as

Supraumbilical Subcutaneous Fat Necrosis After Transcatheter Arterial Chemoembolization with Drug-Eluting Beads: Case Report and Review of the Literature

  • Hee Yeon Kim
  • Si Hyun Bae
  • Chung-Hwa Park
  • Myeong Jun Song
  • Jong Young Choi
  • Seung Kew Yoon
  • Eun Sun Jung
  • Ho Jong ChunEmail author


Recently, transcatheter arterial chemoembolization (TACE) using the drug-eluting embolic microsphere DC Bead (Biocompatibles, Surrey, UK) loaded with doxorubicin resulted in better objective response rates with less systemic complications compared with conventional TACE [1, 2]. A rare but well-known complications of TACE is a supraumbilical skin rash caused by the flow of chemotherapeutic agent into the hepatic falciform artery (HFA). To date, this cutaneous complication was only described for intraarterial chemotherapy infusion or conventional TACE [3, 4, 5]. We present a patient with hepatocellular carcinoma (HCC) who developed subcutaneous fat necrosis of the abdominal wall after TACE with DC Bead.

Case Report

A 70-year-old man with hepatitis C–related liver cirrhosis received two sessions of conventional TACE in 2008 for treating two nodular HCCs in segments 2 and 8. After complete regression of the HCCs, the patient had undergone regular assessments since 2009. In...


Tace Tumor Thrombus Left Portal Vein Skin Complication Portal Vein Flow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2012

Authors and Affiliations

  • Hee Yeon Kim
    • 1
  • Si Hyun Bae
    • 1
  • Chung-Hwa Park
    • 1
  • Myeong Jun Song
    • 1
  • Jong Young Choi
    • 1
  • Seung Kew Yoon
    • 1
  • Eun Sun Jung
    • 2
  • Ho Jong Chun
    • 3
    Email author
  1. 1.Division of Hepatology, Department of Internal MedicineThe Catholic University of KoreaSeocho-gu, SeoulRepublic of Korea
  2. 2.Department of Hospital PathologyThe Catholic University of KoreaSeocho-gu, SeoulRepublic of Korea
  3. 3.Department of Radiology, Seoul St. Mary’s HospitalThe Catholic University of KoreaSeocho-gu, SeoulRepublic of Korea

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