CardioVascular and Interventional Radiology

, Volume 34, Issue 4, pp 676–690 | Cite as

Nanotechnology and its Relationship to Interventional Radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention

  • Sarah Power
  • Michael M. Slattery
  • Michael J. Lee
Review

Abstract

Nanotechnology can be defined as the design, creation, and manipulation of structures on the nanometer scale. This two-part review is intended to acquaint the interventionalist with the field of nanotechnology, and provide an overview of potential applications, while highlighting advances relevant to interventional radiology. Part 2 of the article concentrates on drug delivery, thermotherapy, and vascular intervention. In oncology, advances in drug delivery allow for improved efficacy, decreased toxicity, and greater potential for targeted therapy. Magnetic nanoparticles show potential for use in thermotherapy treatments of various tumours, and the effectiveness of radiofrequency ablation can be enhanced with nanoparticle chemotherapy agents. In vascular intervention, much work is focused on prevention of restenosis through developments in stent technology and systems for localised drug delivery to vessel walls. Further areas of interest include applications for thrombolysis and haemostasis.

Keywords

Nanotechnology Nanoparticle Angiogenesis Thermotherapy Restenosis  Drug delivery 

Notes

Conflict of interest

The authors declare they have no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2010

Authors and Affiliations

  • Sarah Power
    • 1
  • Michael M. Slattery
    • 1
  • Michael J. Lee
    • 1
  1. 1.Department of RadiologyBeaumont HospitalDublin 9Ireland

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