Ruptured Aneurysm of Intercostal Arteriovenous Malformation Associated With Neurofibromatosis Type 1: A Case Report

  • Hyung Jun Kim
  • Hyun Ju SeonEmail author
  • Song Choi
  • Nam Kyu Jang
Case Report


Intercostal arteriovenous malformations (AVM) are rare, with most being secondary to trauma or iatrogenic therapeutic procedures. Only one case of presumably congenital AVM has been reported. Here we report the first case of a ruptured aneurysm of intercostal AVM associated with neurofibromatosis type 1 in a 32-year-old woman who experienced hypovolemic shock caused by massive hemothorax.


Endovascular Treatment Intracranial Aneurysm Neurofibroma Renovascular Hypertension Intercostal Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Conflict of interest

The authors declare that they have no conflict of interest.


  1. 1.
    Riccardi VM (1991) Neurofibromatosis: past, present, and future. N Engl J Med 324(18):1283–1285CrossRefPubMedGoogle Scholar
  2. 2.
    Brasfield RD, Das Gupta TK (1972) Von Recklinghausen’s disease: a clinicopathological study. Ann Surg 175:86–104CrossRefPubMedGoogle Scholar
  3. 3.
    Viskochil D (2002) Genetics of neurofibromatosis 1 and the NF1 gene. J Child Neurol 17:562–570; discussion 571–572, 646–651Google Scholar
  4. 4.
    Reubi F (1945) Neurofibromatose et lesions vascularies. Schweiz Med Wochenschr 75:643–647Google Scholar
  5. 5.
    Friedman JM, Arbiser J, Epstein JA, Gutmann DH, Huot SJ, Lin AE et al (2002) Cardiovascular disease in neurofibromatosis 1: report of the NF1 cardiovascular task force. Genet Med 4:105–111CrossRefPubMedGoogle Scholar
  6. 6.
    Oderich GS, Sullivan TM, Bower TC, Gloviczki P, Miller DV, Babovic-Vuksanovic D et al (2007) Vascular abnormalities in patients with neurofibromatosis syndrome type I: clinical spectrum, management, and results. J Vasc Surg 46:475–484CrossRefPubMedGoogle Scholar
  7. 7.
    Rivera PP, Kole MK, Pelz DM, Gulka IB, McKenzie FN, Lownie SP (2006) Congenital intercostal arteriovenous malformation. AJR Am J Roentgenol 187:W503–W506CrossRefPubMedGoogle Scholar
  8. 8.
    Saitoh S, Matsuda S (1998) Aneurysm of the major vessels in neurofibromatosis. Arch Orthop Trauma Surg 117(1–2):110–113CrossRefPubMedGoogle Scholar
  9. 9.
    Arai K, Sanada J, Kurozumi A, Watanabe T, Matsui O (2007) Spontaneous hemothorax in neurofibromatosis treated with percutaneous embolization. Cardiovasc Interv Radiol 30:477–479CrossRefGoogle Scholar
  10. 10.
    Kanematsu M, Kato H, Kondo H, Goshima S, Tsuge Y, Kojima T et al (2010 April 14) Neurofibromatosis type 1: Transcatheter arterial embolization for ruptured occipital arterial aneurysms. Cardiovasc Interv Radiol. doi: 10.1007/s00270-010-9850-x (Epub ahead of print)
  11. 11.
    Dominguez J, Sancho C, Escalante E, Morera JR, Moya JA, Bernat R (2002) Percutaneous treatment of a ruptured intercostal aneurysm presenting as massive hemothorax in a patient with type I neurofibromatosis. J Thorac Cardiovasc Surg 124:1230–1232CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2010

Authors and Affiliations

  • Hyung Jun Kim
    • 1
  • Hyun Ju Seon
    • 1
    Email author
  • Song Choi
    • 1
  • Nam Kyu Jang
    • 1
  1. 1.Department of RadiologyChonnam National University HospitalDong-guSouth Korea

Personalised recommendations