Abstract
Uterine arteriovenous malformation (AVM) is a rare cause of vaginal bleeding and miscarriage. We report two cases of uterine AVMs in patients with a history of complex congenital heart disease, an association that has not been previously described. Both patients were treated by selective uterine artery embolization, a minimally invasive therapy that has revolutionized the management of uterine AVMs, thus offering an alternative to conventional hysterectomy.
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Grivell RM, Reid KM, Mellor A (2005) Uterine arteriovenous malformations: a review of the current literature. Obstet Gynecol Surv 60:761–767
Arora R, Achla B, Pinkee S et al (2004) Arteriovenous malformations of the uterus. N Z Med J 117(1206):1182
Polat P, Suma S, Kantarcý M et al (2002) Color Doppler US in the evaluation of uterine vascular abnormalities. Radiographics 22:47–53
Rangarajan RD, Moloney JC, Anderson HJ (2007) Diagnosis and nonsurgical management of uterine arteriovenous malformation. Cardiovasc Intervent Radiol 30:1267–1270
Flynn MK, Levine D (1996) The non-invasive diagnosis and management of a uterine arteriovenous malformation. Obstet Gynecol 88:650–652
Takeuchi K, Yamada T, Iwasa M et al (2003) Successful medical treatment with danazol after failed embolization of uterine arteriovenous malformation. Obstet Gynecol 102:843–844
Maleux G, Timmerman D, Heye S et al (2006) Acquired uterine vascular malformations: radiological and clinical outcome after transcatheter embolotherapy. Eur Radiol 16:299–306
Bagga R, Verma P, Aggarwal N et al (2008) Failed angiographic embolization in uterine arteriovenous malformation: a case report and review of the literature. Medscape J Med 10:12
Nicholson AA, Turnbull LW, Coady AM et al (1999) Diagnosis and management of uterine arteriovenous malformations. Clin Radiol 54:265–269
McCormick CC, Kim HS (2006) Successful pregnancy with a full-term vaginal delivery one year after n-butyl cyanoacrylate embolization of a uterine arteriovenous malformation. Cardiovasc Intervent Radiol 29:699–701
Presbitero P, Somerville J, Stone S et al (1994) Pregnancy in cyanotic congenital heart disease. Outcome of mother and fetus. Circulation 89:2673–2676
Ticho BS, Goldstein AM, Van Praagh R (2000) Extracardiac anomalies in the heterotaxy syndromes with focus on anomalies of midline-associated structures. Am J Cardiol 85:729–734
Srivastava D, Preminger T, Lock JE et al (1996) Hepatic venous blood and the development of pulmonary arteriovenous malformations in congenital heart disease. Circulation 92:1217–1222
Dodge-Khatami A, Sreeram N, de Mol BA et al (2003) Systemic plasma vascular endothelial growth factor levels as a marker for increased angiogenesis during the single ventricle surgical pathway. Interact Cardiovasc Thorac Surg 2:458–461
Starnes SL, Duncan BW, Kneebone JM et al (2000) Vascular endothelial growth factor and basic fibroblast growth factor in children with cyanotic congenital heart disease. J Thorac Cardiovasc Surg 119:534–539
Starnes SL, Duncan BW, Kneebone JM et al (2001) Angiogenic proteins in the lungs of children after cavopulmonary anastomosis. J Thorac Cardiovasc Surg 122:518–523
Cirulli A, Liso A, D’Ovidio F et al (2003) Vascular endothelial growth factor serum levels are elevated in patients with hereditary hemorrhagic telangiectasia. Acta Haematol 110:29–32
Dahlgren LS, Effer SB, McGillivray BC et al (2006) Pregnancy with uterine vascular malformations associated with hemorrhagic hereditary telangiectasia: a case report. J Obstet Gynaecol Can 28:720–723
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Wijesekera, N.T., Padley, S.P., Kazmi, F. et al. Embolization of Uterine Arteriovenous Malformations Associated with Cyanotic Congenital Heart Disease. Cardiovasc Intervent Radiol 32, 1075–1079 (2009). https://doi.org/10.1007/s00270-009-9573-z
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DOI: https://doi.org/10.1007/s00270-009-9573-z