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CardioVascular and Interventional Radiology

, Volume 32, Issue 4, pp 714–719 | Cite as

Telemetric Catheter-Based Pressure Sensor for Hemodynamic Monitoring: Experimental Experience

  • Andreas H. MahnkenEmail author
  • Ute Urban
  • Holger Fassbender
  • Uwe Schnakenberg
  • Felix Schoth
  • Thomas Schmitz-Rode
Laboratory Investigation

Abstract

The purpose of this study was to evaluate the technical and animal experimental feasibility of a percutaneously implantable pulmonary arterial implant for permanent hemodynamic monitoring. Two systems for measuring pulmonary artery pressure (PAP) as well as pulmonary artery occlusion pressure (PAOP) were developed by modifying a commercially available pulmonary artery catheter (PAC). First, a cable-bound catheter-based system was designed by implementation of a capacitive absolute-pressure sensor in the catheter tip. This system was developed further into a completely implantable telemetric system. The devices were tested in an acute setting in a total of 10 sheep. The implant was placed with its tip in the descending pulmonary artery via the right jugular approach. Results were compared with conventional PAC positioned in the contralateral pulmonary artery using Pearson’s correlation coefficients and Bland-Altman plots. Implantation of the monitoring systems was uneventful in 10 animals. Data from two fully functional cable-bound and telemetric pressure monitoring systems were available, with a total of 18,506 measurements. There was an excellent correlation between reference data and the data obtained with the implants (r = 0.9944). Bland-Altman plots indicated a very good agreement between the techniques. We report the development and successful initial test of an implantable catheter-based device for long-term measurement of PAP and PAOP. Both devices may be applicable for hemodynamic monitoring. Further long-term studies for assessing reliability and durability of the device are warranted.

Keywords

Pulmonary artery catheter Implant Hemodynamic monitoring 

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Copyright information

© Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) 2009

Authors and Affiliations

  • Andreas H. Mahnken
    • 1
    • 2
    • 4
    Email author
  • Ute Urban
    • 2
  • Holger Fassbender
    • 3
  • Uwe Schnakenberg
    • 3
  • Felix Schoth
    • 1
  • Thomas Schmitz-Rode
    • 2
  1. 1.Department of Diagnostic RadiologyAachen University HospitalAachenGermany
  2. 2.Applied Medical Engineering, Helmholtz InstituteRWTH Aachen UniversityAachenGermany
  3. 3.Institute of Materials in Electrical Engineering 1RWTH Aachen UniversityAachenGermany
  4. 4.University Hospital, RWTH Aachen UniversityAachenGermany

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