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First Magnetic Resonance Imaging-Guided Aortic Stenting and Cava Filter Placement Using a Polyetheretherketone-Based Magnetic Resonance Imaging-Compatible Guidewire in Swine: Proof of Concept

  • Sebastian Kos
  • Rolf Huegli
  • Eugen Hofmann
  • Harald H. Quick
  • Hilmar Kuehl
  • Stephanie Aker
  • Gernot M. Kaiser
  • Paul J. A. Borm
  • Augustinus L. Jacob
  • Deniz Bilecen
Technical Note

Abstract

The purpose of this study was to demonstrate feasibility of percutaneous transluminal aortic stenting and cava filter placement under magnetic resonance imaging (MRI) guidance exclusively using a polyetheretherketone (PEEK)-based MRI-compatible guidewire. Percutaneous transluminal aortic stenting and cava filter placement were performed in 3 domestic swine. Procedures were performed under MRI-guidance in an open-bore 1.5-T scanner. The applied 0.035-inch guidewire has a PEEK core reinforced by fibres, floppy tip, hydrophilic coating, and paramagnetic markings for passive visualization. Through an 11F sheath, the guidewire was advanced into the abdominal (swine 1) or thoracic aorta (swine 2), and the stents were deployed. The guidewire was advanced into the inferior vena cava (swine 3), and the cava filter was deployed. Postmortem autopsy was performed. Procedural success, guidewire visibility, pushability, and stent support were qualitatively assessed by consensus. Procedure times were documented. Guidewire guidance into the abdominal and thoracic aortas and the inferior vena cava was successful. Stent deployments were successful in the abdominal (swine 1) and thoracic (swine 2) segments of the descending aorta. Cava filter positioning and deployment was successful. Autopsy documented good stent and filter positioning. Guidewire visibility through applied markers was rated acceptable for aortic stenting and good for venous filter placement. Steerability, pushability, and device support were good. The PEEK-based guidewire allows either percutaneous MRI-guided aortic stenting in the thoracic and abdominal segments of the descending aorta and filter placement in the inferior vena cava with acceptable to good device visibility and offers good steerability, pushability, and device support.

Keywords

Interventional radiology MR-intervention Guide wire PEEK MR-guided stenting MR-compatible Cava filter 

Notes

Acknowledgments

This study was designed as a first-proof concept study in swine. Of course, further investigation is necessary to determine the potential of this new PEEK-based guidewire for MRI-guided arterial and venous interventions.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Sebastian Kos
    • 1
  • Rolf Huegli
    • 2
  • Eugen Hofmann
    • 3
  • Harald H. Quick
    • 4
  • Hilmar Kuehl
    • 4
  • Stephanie Aker
    • 5
  • Gernot M. Kaiser
    • 6
  • Paul J. A. Borm
    • 7
  • Augustinus L. Jacob
    • 1
  • Deniz Bilecen
    • 1
  1. 1.Institute of RadiologyUniversity Hospital BaselBaselSwitzerland
  2. 2.Institute of RadiologyKantonsspital BruderholzBruderholzSwitzerland
  3. 3.Vascular InterventionBiotronikBuelachSwitzerland
  4. 4.Department of Diagnostic and Interventional Radiology and NeuroradiologyUniversity of Duisburg-EssenEssenGermany
  5. 5.Institute of PathophysiologyUniversity of Duisburg-EssenEssenGermany
  6. 6.Department of General, Visceral, and Transplantation SurgeryUniversity of Duisburg-EssenEssenGermany
  7. 7.MagnaMedics GmbHAachenGermany

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