CardioVascular and Interventional Radiology

, Volume 32, Issue 2, pp 329–332 | Cite as

Fibromuscular Dysplasia Presenting with Bilateral Renal Infarction

  • O. DoodyEmail author
  • W. R. Adam
  • P. T. Foley
  • S. M. Lyon
Case Report


Fibromuscular dysplasia (FMD) describes a group of conditions which cause nonatheromatous arterial stenoses, most commonly of the renal and carotid arteries, typically in young women. We report a rare case of bilateral segmental renal infarction secondary to FMD in a young male patient. His initial presentation with loin pain and pyrexia resulted in a delay in the definitive diagnosis of FMD. He was successfully treated with bilateral balloon angioplasty. The delayed diagnosis in this patient until the condition had progressed to bilateral renal infarcts highlights the need for prompt investigation and diagnosis of suspected cases of FMD.


Fibromuscular dysplasia Renal infarction Angioplasty Renal scarring 


  1. 1.
    Lüscher TF, Lie JT, Stanson AW et al (1987) Arterial fibromuscular dysplasia. Mayo Clin Proc 62(10):931–952PubMedGoogle Scholar
  2. 2.
    Slovut DP, Olin JW (2004) Fibromuscular dysplasia. N Engl J Med 350(18):1862–7181PubMedCrossRefGoogle Scholar
  3. 3.
    Salifu MO, Gordon DH, Friedman EA et al (2000) Bilateral renal infarction in a black man with medial fibromuscular dysplasia. Am J Kidney Dis 36(1):184–189PubMedCrossRefGoogle Scholar
  4. 4.
    Stinchcombe SJ, Manhire AR, Bishop MC et al (1992) Renal arterial fibromuscular dysplasia: acute renal infarction in three patients with angiographic evidence of medial fibroplasia. Br J Radiol 65(769):81–84PubMedCrossRefGoogle Scholar
  5. 5.
    Siegelbaum MH, Weiss JP (1990) Renal infarction secondary to fibrous dysplasia and aneurysm formation of renal artery. Urology 35(1):73–75PubMedCrossRefGoogle Scholar
  6. 6.
    Barbey F, Matthieu C, Nseir G et al (2003) A young man with a renal colic. J Intern Med 254(6):605–608PubMedCrossRefGoogle Scholar
  7. 7.
    Stewart BH, Dustan HP, Kiser WS et al (1970) Correlation of angiography and natural history in evaluation of patients with renovascular hypertension. J Urol 104(2):231–238PubMedGoogle Scholar
  8. 8.
    Harrison EG Jr, McCormack LJ (1971) Pathologic classification of renal arterial disease in renovascular hypertension. Mayo 46(3):161–167Google Scholar
  9. 9.
    Kincaid OW, Davis GD, Hallermann FJ et al (1968) Fibromuscular dysplasia of the renal arteries. Arteriographic features, classification, and observations on natural history of the disease. Am J Roentgenol Radium Ther Nucl Med 104(2):271–282PubMedGoogle Scholar
  10. 10.
    Begelman SM, Olin JW (2000) Fibromuscular dysplasia. Curr Opin Rheumatol 12(1):41–47PubMedCrossRefGoogle Scholar
  11. 11.
    Stanley JC, Gewertz BL, Bove EL et al (1975) Arterial fibrodysplasia. Histopathologic character and current etiologic concepts. Arch Surg 110(5):561–566PubMedGoogle Scholar
  12. 12.
    Stanley JC (1996) Renal artery fibrodysplasia. In: Novick AC, Scable J, Hamilton G (eds) Renal vascular disease. WB Saunders, London, pp 21–23Google Scholar
  13. 13.
    Alimi Y, Mercier C, Péllissier JF et al (1992) Fibromuscular disease of the renal artery: a new histopathologic classification. Ann Vasc Surg 6(3):220–224PubMedCrossRefGoogle Scholar
  14. 14.
    Safian RD, Textor SC (2001) Renal-artery stenosis. N Engl J Med 344(6):431–442PubMedCrossRefGoogle Scholar
  15. 15.
    Goncharenko V, Gerlock AJ Jr, Shaff MI et al (1981) Progression of renal artery fibromuscular dysplasia in 42 patients as seen on angiography. Radiology 139(1):45–51PubMedGoogle Scholar
  16. 16.
    Sinnamon K, McNally D, Harty J (2007) Fibromuscular dysplasia presenting as renal infarction. Kidney Int 72(10):1295–1296PubMedCrossRefGoogle Scholar
  17. 17.
    Domanovits H, Paulis M, Nikfardjam M et al (1999) Acute renal infarction. Clinical characteristics of 17 patients. Medicine (Baltimore) 78(6):386–394CrossRefGoogle Scholar
  18. 18.
    Chu P, Wei Y, Huang J et al (2006) Clinical characteristics of patients with segmental renal infarction. Nephrology 11(4):336–340PubMedCrossRefGoogle Scholar
  19. 19.
    Sabharwal R, Viatica P, Coleman P (2007) Multidetector spiral CT renal angiography in the diagnosis of renal artery fibromuscular dysplasia. Eur J Radiol 61(3):520–527PubMedCrossRefGoogle Scholar
  20. 20.
    de Fraissinette B, Garcier JM, Dieu V et al (2003) Percutaneous transluminal angioplasty of dysplastic stenoses of the renal artery: results on 70 adults. CardioVasc Interv Radiol 26(1):46–51CrossRefGoogle Scholar
  21. 21.
    Tanaka R, Higashi M, Naito H (2007) Angioplasty for non-arteriosclerotic renal artery stenosis: the efficacy of cutting balloon angioplasty versus conventional angioplasty. CardioVasc Interv Radiol 30(4):601–606CrossRefGoogle Scholar
  22. 22.
    Tanemoto M, Abe T, Chaki T et al (2005) Cutting balloon angioplasty of resistant renal artery stenosis caused by fibromuscular dysplasia. J Vasc Surg 41(5):898–901PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • O. Doody
    • 1
    Email author
  • W. R. Adam
    • 2
  • P. T. Foley
    • 1
  • S. M. Lyon
    • 1
    • 3
  1. 1.Department of RadiologyThe Alfred HospitalMelbourneAustralia
  2. 2.School of Rural HealthUniversity of Melbourne and Goulburn Valley HealthSheppartonAustralia
  3. 3.Department of MedicineMonash Medical School, The Alfred HospitalMelbourneAustralia

Personalised recommendations