Advertisement

World Journal of Surgery

, Volume 21, Issue 8, pp 811–815 | Cite as

Antibiotic Prophylaxis and Open Groin Hernia Repair

  • Eric W. Taylor
  • Derek J. Byrne
  • David J. Leaper
  • Stephan J. Karran
  • M. Kennedy Browne
  • Kenneth J. Mitchell

Abstract. Antibiotic prophylaxis is not routinely given for nonimplant, clean operations, although this view has recently been challenged. We have conducted a randomized multicenter, double-blind prospective trial to compare co-amoxiclav with placebo in 619 patients undergoing open groin hernia repair. Altogether 563 (91%) patients fulfilled the protocol; 283 received co-amoxiclav and 280 placebo. There was no difference between the groups in the number of patients receiving local or general anesthetic, the type of repair performed, the use of a subcutaneous fat suture, the type of skin closure used, the use of wound analgesia, or the use of a wound drain. Patients were given a card to return to the hospital in the event of their wound discharging or their needing to see their general practitioner. All patients were reviewed at approximately 6 weeks after operation. Fifty (8.9%) patients sustained a wound infection, 25 in the co-amoxiclav group and 25 in the placebo group. We conclude that antibiotic prophylaxis is of no benefit to patients undergoing open groin hernia repair.

Keywords

Placebo Placebo Group General Practitioner Wound Infection Hernia Repair 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Société Internationale de Chirugie 1997

Authors and Affiliations

  • Eric W. Taylor
    • 1
  • Derek J. Byrne
    • 2
  • David J. Leaper
    • 3
  • Stephan J. Karran
    • 4
  • M. Kennedy Browne
    • 5
  • Kenneth J. Mitchell
    • 6
  1. 1.Vale of Leven District General Hospital, Alexandria Dunbartonshire G83 OUA, Scotland, UKGB
  2. 2.Ninewells Hospital, Dundee DD2 1UB, Scotland, UKGB
  3. 3.Southmead Hospital, Westbury-on-Trym, Bristol BS10 5N, England, UKGB
  4. 4.Southampton General Hospital, Tremona Road, Southampton S09 4XY, England, UKGB
  5. 5.Monklands Hospital, Monkscourt Avenue, Airdrie ML6 OJS, Scotland, UKGB
  6. 6.Royal Alexandra Hospital, Corsebar Road, Paisley PA2 9PL, Scotland, UKGB

Personalised recommendations