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Usefulness of a 3D-Printed Thyroid Cancer Phantom for Clinician to Patient Communication

  • Dayeong Hong
  • Sangwook Lee
  • Taehun Kim
  • Jung Hwan Baek
  • Won Woong Kim
  • Ki-Wook Chung
  • Namkug KimEmail author
  • Tae-Yon SungEmail author
Original Scientific Report

Abstract

Background

Thyroid glands and surrounding structures are very complex, and this complexity can pose a challenge for clinicians when explaining and communicating to the patient the details of a proposed surgery for thyroid cancer. A three-dimensional (3D) thyroid cancer model could help and improve this communication.

Methods

A 3D-printed phantom of a thyroid gland and its presenting cancer was produced from segmented head and neck contrast-enhanced computed tomography (CT) data from a patient with thyroid cancer. The phantom reflects the complex anatomy of the arteries, veins, nerves, and other surrounding organs, and the printing materials and techniques were adjusted to represent the texture and color of the actual structures. Using this phantom, patients and clinicians completed surveys on the usefulness of this 3D-printed thyroid cancer phantom. Participants: patients (n = 33) and clinicians (n = 10).

Results

In the patient survey, the patients communicated that the quality of understanding of their thyroid disease status was enhanced when clinicians explained using the phantom. The clinicians communicated that the 3D phantom was advantageous for explaining complex thyroid surgery procedures to patients, and that the 3D phantom was helpful in educating patients with relatively poor anatomical knowledge.

Conclusions

Using 3D printing technology, we produced a CT-based 3D thyroid cancer phantom, and patient and clinician surveys on its utility indicated that it successfully helped educate patients, providing them with an improved understanding of the disease.

Notes

Funding

None declared by all authors except Namkug Kim who is a stockholder of Anymedi Inc, South Korea. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

References

  1. 1.
    Durante C, Montesano T, Torlontano M et al (2013) Papillary thyroid cancer: time course of recurrences during postsurgery surveillance. J Clin Endocrinol Metab 98:636–642CrossRefGoogle Scholar
  2. 2.
    Cho BY, Choi HS, Park YJ et al (2013) Changes in the clinicopathological characteristics and outcomes of thyroid cancer in Korea over the past four decades. Thyroid 23:797–804CrossRefGoogle Scholar
  3. 3.
    Sampson E, Brierley JD, Le LW et al (2007) Clinical management and outcome of papillary and follicular (differentiated) thyroid cancer presenting with distant metastasis at diagnosis. Cancer 110:1451–1456CrossRefGoogle Scholar
  4. 4.
    Kim H, Kim HI, Kim SW et al (2018) Prognosis of differentiated thyroid carcinoma with initial distant metastasis: a multicenter study in Korea. Endocrinol Metab (Seoul) 33:287–295CrossRefGoogle Scholar
  5. 5.
    Samaan NA, Schultz PN, Hickey RC et al (1992) The results of various modalities of treatment of well differentiated thyroid carcinomas: a retrospective review of 1599 patients. J Clin Endocrinol Metab 75:714–720PubMedGoogle Scholar
  6. 6.
    Hay ID, Hutchinson ME, Gonzalez-Losada T et al (2008) Papillary thyroid microcarcinoma: a study of 900 cases observed in a 60-year period. Surgery 144:980–987 (discussion 987–988) CrossRefGoogle Scholar
  7. 7.
    Kim YS, Choi JH, Kim KS et al (2017) The role of adjuvant external beam radiation therapy for papillary thyroid carcinoma invading the trachea. Radiat Oncol J 35:112–120CrossRefGoogle Scholar
  8. 8.
    Wang LY, Nixon IJ, Patel SG et al (2016) Operative management of locally advanced, differentiated thyroid cancer. Surgery 160:738–746CrossRefGoogle Scholar
  9. 9.
    Mazzaferri EL, Jhiang SM (1994) Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. Am J Med 97:418–428CrossRefGoogle Scholar
  10. 10.
    Haugen BR (2017) 2015 american thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: What is new and what has changed? Cancer 123:372–381CrossRefGoogle Scholar
  11. 11.
    Qiu K, Haghiashtiani G, McAlpine MC (2018) 3D printed organ models for surgical applications. Ann Rev Anal Chem 11:287–306CrossRefGoogle Scholar
  12. 12.
    Kim GB, Lee S, Kim H et al (2016) Three-dimensional printing: basic principles and applications in medicine and radiology. Korean J Radiol 17:182–197CrossRefGoogle Scholar
  13. 13.
    Bücking TM, Hill ER, Robertson JL et al (2017) From medical imaging data to 3D printed anatomical models. PLoS ONE 12:e0178540CrossRefGoogle Scholar
  14. 14.
    Hong D, Lee S, Kim T et al (2019) Development of a personalized and realistic educational thyroid cancer phantom based on CT images: an evaluation of accuracy between three different 3D printers. Comput Biol Med 113:103393CrossRefGoogle Scholar
  15. 15.
    Brown CL, Hartman RP, Dzyubak OP et al (2009) Dual-energy CT iodine overlay technique for characterization of renal masses as cyst or solid: a phantom feasibility study. Eur Radiol 19:1289–1295CrossRefGoogle Scholar
  16. 16.
    Kim MS, Hansgen AR, Carroll JD (2008) Use of rapid prototyping in the care of patients with structural heart disease. Trends Cardiovasc Med 18:210–216CrossRefGoogle Scholar
  17. 17.
    Kim EY, Kim TY, Kim WG et al (2011) Effects of different doses of radioactive iodine for remnant ablation on successful ablation and on long-term recurrences in patients with differentiated thyroid carcinoma. Nucl Med Commun 32:954–959CrossRefGoogle Scholar
  18. 18.
    Doucet G, Ryan S, Bartellas M et al (2017) Modelling and manufacturing of a 3D printed trachea for cricothyroidotomy simulation. Cureus 9:e1575.  https://doi.org/10.7759/cureus.1575 CrossRefPubMedPubMedCentralGoogle Scholar
  19. 19.
    Lim PK, Stephenson GS, Keown TW et al (2018) Use of 3D printed models in resident education for the classification of acetabulum fractures. J Surg Educ 75:1679–1684CrossRefGoogle Scholar
  20. 20.
    AlAli AB, Griffin MF, Calonge WM et al (2018) Evaluating the use of cleft lip and palate 3D-printed models as a teaching aid. J Surg Educ 75:200–208CrossRefGoogle Scholar
  21. 21.
    Martins P, Natal Jorge R, Ferreira A (2006) A comparative study of several material models for prediction of hyperelastic properties: application to silicone-rubber and soft tissues. Strain 42:135–147CrossRefGoogle Scholar
  22. 22.
    Madsen EL, Hobson MA, Shi H et al (2005) Tissue-mimicking agar/gelatin materials for use in heterogeneous elastography phantoms. Phys Med Biol 50:5597CrossRefGoogle Scholar

Copyright information

© Société Internationale de Chirurgie 2019

Authors and Affiliations

  • Dayeong Hong
    • 1
  • Sangwook Lee
    • 1
  • Taehun Kim
    • 1
  • Jung Hwan Baek
    • 2
  • Won Woong Kim
    • 3
  • Ki-Wook Chung
    • 3
  • Namkug Kim
    • 1
    • 2
    Email author
  • Tae-Yon Sung
    • 3
    Email author
  1. 1.Department of Biomedical Engineering, Asan Medical Institute of Convergence Science and Technology, Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea
  2. 2.Department of Radiology, Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea
  3. 3.Department of Surgery, Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea

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