Abstract
Background
Metrics to measure the burden of surgical conditions, such as disability weights (DWs), are poorly defined, particularly for pediatric conditions. To summarize the literature on DWs of children’s surgical conditions, we performed a systematic review of disability weights of pediatric surgical conditions in low- and middle-income countries (LMICs).
Method
For this systematic review, we searched MEDLINE for pediatric surgery cost-effectiveness studies in LMICs, published between January 1, 1996, and April 1, 2017. We also included DWs found in the Global Burden of Disease studies, bibliographies of studies identified in PubMed, or through expert opinion of authors (ES and HR).
Results
Out of 1427 publications, 199 were selected for full-text analysis, and 30 met all eligibility criteria. We identified 194 discrete DWs published for 66 different pediatric surgical conditions. The DWs were primarily derived from the Global Burden of Disease studies (72%). Of the 194 conditions with reported DWs, only 12 reflected pre-surgical severity, and 12 included postsurgical severity. The methodological quality of included studies and DWs for specific conditions varied greatly.
Interpretation
It is essential to accurately measure the burden, cost-effectiveness, and impact of pediatric surgical disease in order to make informed policy decisions. Our results indicate that the existing DWs are inadequate to accurately quantify the burden of pediatric surgical conditions. A wider set of DWs for pediatric surgical conditions needs to be developed, taking into account factors specific to the range and severity of surgical conditions.
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Acknowledgements
We want to thank the Global Initiative for Children’s Surgery (GICS) for its support of this work. GICS (www.globalchildrenssurgery.org) is a network of children’s surgical and anesthesia providers from low-, middle-, and high-income countries collaborating for the purpose of improving the quality of surgical care for children globally.
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Duke Global Health Institute.
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MGS receives support from the GE Foundation Safe Surgery 2020 project and from the Damon Runyon Cancer Research Foundation. No specific funding was obtained for this paper.
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Smith, E.R., Concepcion, T., Lim, S. et al. Disability Weights for Pediatric Surgical Procedures: A Systematic Review and Analysis. World J Surg 42, 3021–3034 (2018). https://doi.org/10.1007/s00268-018-4537-6
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DOI: https://doi.org/10.1007/s00268-018-4537-6