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Impaired Gastrointestinal Function Affects Symptoms and Alimentary Status in Patients After Gastrectomy

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Abstract

Background

Postgastrectomy syndrome (PGS) remains a common complication after gastrectomy that affects patients’ quality of life. Although impaired gastrointestinal (GI) function by gastrectomy procedures is thought to be the cause, the precise pathophysiology of PGS is yet to be clarified.

Aim

The aim of this study was to investigate relationships between GI function and various symptoms or alimentary status in patients after gastrectomy.

Methods

Fifty-one patients who underwent total or distal gastrectomy at least 1 year previously were studied. All patients replied to a questionnaire that asked presence of symptoms (esophageal reflux, nausea, abdominal pain, early satiation, diarrhea, early dumping general, early dumping abdominal, and late dumping symptoms) and alimentary status (change in body weight, food intake per meal, frequency of meals per day). They also underwent assessment of GI function consisting of gastric emptying study by 13C-acetate breath test to examine reservoir capacity and gastric emptying, and water load drink test to evaluate tolerance to volume loading (TVL). The relationships between GI function and each symptom or alimentary status were examined.

Results

The patients with nausea and early dumping general symptoms had significantly smaller reservoir capacity*, the patients with diarrhea and early dumping general symptoms had significantly faster gastric emptying*, and the patients with early satiation and early dumping abdominal symptoms had significantly impaired TVL*. Significant correlations were identified between TVL and body weight changes* or food intake per meal* (* p < 0.05).

Conclusion

Impaired postoperative GI function was closely related to symptoms or worse alimentary status.

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Authors and Affiliations

  1. Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan

    Hideo Konishi, Koji Nakada, Masahiko Kawamura, Taizo Iwasaki, Keishiro Murakami, Norio Mitsumori & Katsuhiko Yanaga

Authors
  1. Hideo Konishi
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  2. Koji Nakada
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  3. Masahiko Kawamura
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  4. Taizo Iwasaki
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  5. Keishiro Murakami
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  6. Norio Mitsumori
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  7. Katsuhiko Yanaga
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Correspondence to Hideo Konishi.

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Konishi, H., Nakada, K., Kawamura, M. et al. Impaired Gastrointestinal Function Affects Symptoms and Alimentary Status in Patients After Gastrectomy. World J Surg 40, 2713–2718 (2016). https://doi.org/10.1007/s00268-016-3613-z

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  • DOI: https://doi.org/10.1007/s00268-016-3613-z

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