World Journal of Surgery

, Volume 35, Issue 2, pp 458–459 | Cite as

Managing BRCA Mutation Carriers in China



  1. 1.
    Kwong A, Wong CH, Shea C et al (2010) Choice of management of southern Chinese BRCA mutation carriers. World J Surg 34:1416–1426CrossRefPubMedGoogle Scholar
  2. 2.
    Ziogas D, Roukos DH (2009) Genetics and personal genomics for personalized breast cancer surgery: progress and challenges in research and clinical practice. Ann Surg Oncol 16:1771–1782CrossRefPubMedGoogle Scholar
  3. 3.
    Metcalfe KA, Lubinski J, Ghadirian P et al (2008) Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group. J Clin Oncol 26:1093–1097CrossRefPubMedGoogle Scholar
  4. 4.
    Roukos DH (2009) Breast cancer outcomes: the crucial role of the breast surgeon in the era of personal genetics and systems biology. Ann Surg 249(6):1067–1068CrossRefPubMedGoogle Scholar
  5. 5.
    Roukos DH, Ziogas D (2010) From tumor size and HER2 status to systems oncology for very early breast cancer treatment. Expert Rev Anticancer Ther 10(2):123–128CrossRefPubMedGoogle Scholar
  6. 6.
    Roukos DH, Ziogas DE, Katsios C (2010) Multigene assays and isolated tumor cells for early breast cancer treatment: time for bionetworks. Expert Rev Anticancer Ther 10(8):1187–1195CrossRefPubMedGoogle Scholar
  7. 7.
    Roukos DH (2010) Complete genome sequencing and network modeling to overcome trastuzumab resistance. Pharmacogenomics 11(8):1039–1043CrossRefPubMedGoogle Scholar
  8. 8.
    Roukos DH (2010) Next-generation, genome sequencing-based biomarkers: concerns and challenges for medical practice. Biomark Med 4(4):583–586CrossRefPubMedGoogle Scholar
  9. 9.
    Katsios C, Roukos DH (2010) Individual genomes and personalized medicine: life diversity and complexity. Per Med 7(4): 347–350CrossRefGoogle Scholar
  10. 10.
    Roukos DH, Katsios C, Liakakos T (2010) Genotype-phenotype map and molecular networks: a promising solution in overcoming colorectal cancer resistance to targeted treatment. Expert Rev Mol Diagn 10(5):541–545CrossRefPubMedGoogle Scholar
  11. 11.
    Roukos DH (2009) Radiation therapy for breast cancer. N Engl J Med 360(13):1362; author reply 1363CrossRefPubMedGoogle Scholar
  12. 12.
    Roukos DH (2010) Systems medicine: a real approach for future personalized oncology? Pharmacogenomics 11(3):283–287CrossRefPubMedGoogle Scholar
  13. 13.
    Roukos DH (2010) Novel clinico-genome network modeling for revolutionizing genotype-phenotype-based personalized cancer care. Expert Rev Mol Diagn 10(1):33–48CrossRefPubMedGoogle Scholar
  14. 14.
    Roukos DH (2009) Isolated tumor cells in breast cancer. N Engl J Med 361:1994–1995; author reply 1995–1996CrossRefPubMedGoogle Scholar
  15. 15.
    Roukos DH, Tzakos A, Zografos G (2009) Current concerns and challenges towards tailored anti-angiogenic therapy in cancer. Expert Rev Anticancer Ther 9(10):1413–1416CrossRefPubMedGoogle Scholar

Copyright information

© Société Internationale de Chirurgie 2010

Authors and Affiliations

  1. 1.Department of Surgery (Breast Cancer Unit)“METAXA” Cancer Memorial HospitalPiraeusGreece

Personalised recommendations