World Journal of Surgery

, Volume 34, Issue 7, pp 1548–1554 | Cite as

Risk Factors for Metachronous Gastric Cancer in the Remnant Stomach After Early Cancer Surgery

  • Isao Nozaki
  • Junichirou Nasu
  • Yoshiro Kubo
  • Minoru Tanada
  • Rieko Nishimura
  • Akira Kurita
Article

Abstract

Background

Early gastric cancer patients have a good prognosis after radical resection. However, if the patients have a gastric remnant after the surgery, the risk of metachronous gastric cancer remains. The aim of this study was to clarify the risk factors for metachronous gastric cancer after partial gastrectomy for early gastric cancer.

Methods

Data on a series of 1281 consecutive gastrectomy patients with pathologically confirmed early gastric cancer from 1991 to 2007 in Shikoku Cancer Center were analyzed retrospectively.

Results

The gastric remnants of 868 patients were periodically surveyed by endoscopic examination. Among those surveyed cases, 26 patients were diagnosed as having metachronous gastric cancer in the gastric remnant. They underwent curative resection by remnant gastrectomy (n = 13 patients) or endoscopic mucosal resection (n = 13 patients). Multivariate analysis showed that male sex, older age, submucosal invasion, and proximal gastrectomy were independent risk factors.

Conclusions

Our data suggested that more intensive endoscopic follow-up is needed for the remnant stomach in patients with these risk factors to detect metachronous gastric cancer at its early stage.

Notes

Acknowledgments

We thank Dr. Koji Ohta and Dr. Takaya Kobatake, who gave us insightful comments and suggestions for this study.

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Copyright information

© Société Internationale de Chirurgie 2010

Authors and Affiliations

  • Isao Nozaki
    • 1
  • Junichirou Nasu
    • 2
  • Yoshiro Kubo
    • 1
  • Minoru Tanada
    • 1
  • Rieko Nishimura
    • 3
  • Akira Kurita
    • 1
  1. 1.Department of Surgery, Division of Gastroenterology, National Hospital OrganizationShikoku Cancer CenterMatsuyamaJapan
  2. 2.Department of Internal Medicine, National Hospital OrganizationShikoku Cancer CenterMatsuyamaJapan
  3. 3.Department of Pathology, National Hospital OrganizationShikoku Cancer CenterMatsuyamaJapan

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