World Journal of Surgery

, Volume 31, Issue 9, pp 1883–1888 | Cite as

Typhoid Intestinal Perforations: Twenty-six Year Experience

  • S. Selcuk AtamanalpEmail author
  • Bulent Aydinli
  • Gurkan Ozturk
  • Durkaya Oren
  • Mahmut Basoglu
  • M. Ilhan Yildirgan



Typhoid fever (TF) is a severe febrile illness caused by Salmonella typhi. One of the most lethal complications of TF is ileal perforation (TIP). Although the mortality of associated with TIP has decreased slightly over the past decade, it is still high.

Methods and Results

The records of the 82 surgically treated patients with TIP were evaluated retrospectively. There were 64 men with the mean age of 36.3 years (range: 7–68 years). In surgical treatment, debridement with primary closure was performed in 32 patients (39.0%), and wedge resection with primary closure was performed in 9 (11. 0%), resection with primary anastomosis in 9 (11.0%), and resection with ileostomy in 32 (39.0%). The most common postoperative complication was wound infection, which occurred in 24 patients (29.3%). The overall morbidity was highest in the ileostomy group. The overall mortality was 11.0% (9 patients). Age, gender, number, and localization of the perforations (p > 0.05) were not found to affect mortality, but prolonged preoperative period (p < 0.001), extended peritoneal contamination (p < 0.01), and ileostomy procedure (p < 0.001) were found to influence the increase in mortality.


Early and appropriate surgical intervention with effective preoperative and postoperative care may improve survival in TIP.


Typhoid Fever Primary Closure Primary Anastomosis Ileocecal Valve Fecal Fistula 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Société Internationale de Chirurgie 2007

Authors and Affiliations

  • S. Selcuk Atamanalp
    • 1
    Email author
  • Bulent Aydinli
    • 1
  • Gurkan Ozturk
    • 1
  • Durkaya Oren
    • 1
  • Mahmut Basoglu
    • 1
  • M. Ilhan Yildirgan
    • 1
  1. 1.Department of General SurgeryAtatürk University, School of MedicineErzurumTurkey

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