World Journal of Surgery

, Volume 29, Issue 12, pp 1592–1599 | Cite as

Proximal Gastrectomy Reconstructed by Jejunal Pouch Interposition for Upper Third Gastric Cancer: Prospective Randomized Study

  • Chang Hak YooEmail author
  • Byung Ho Sohn
  • Won Kon Han
  • Won Kil Pae


Proximal gastrectomy with jejunal pouch interposition (PGJP) has been advocated as an alternative operation for upper third gastric cancer. However, there has been no prospective randomized trial comparing PGJP with total gastrectomy with Roux-en-Y esophagojejunostomy (TGRY). The aim of this study was to compare the short- and medium-term results of PGJP and TGRY in a randomized clinical trial. Fifty-one patients with upper third gastric cancer were randomized to either PGJP (n = 25) or TGRY (n = 26). Outcome measures were postoperative complications, nutritional status assessed by serum nutritional parameters, and postgastrectomy symptoms. There were no significant differences in operating time, hospital stay, and postoperative complications. Blood loss was significantly less in the PGJP group (P = 0.036). Nineteen patients (73%) in the TGRY group had one or more postgastrectomy symptoms, which was significantly more frequent than in the PGJP group (32%; P = 0.012). There were also significant differences between the two groups with regard to food intake, weight recovery, hemoglobin, and serum vitamin B12 levels in favor of PGJP. In conclusion, proximal gastrectomy with jejunal pouch interposition for upper third gastric cancer is safe, and is associated with a greater reduction in postgastrectomy symptoms and better nutritional status compared with conventional total gastrectomy.


Gastric Cancer Total Gastrectomy Reflux Esophagitis Remnant Stomach Proximal Gastrectomy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Société Internationale de Chirurgie 2005

Authors and Affiliations

  • Chang Hak Yoo
    • 1
    Email author
  • Byung Ho Sohn
    • 1
  • Won Kon Han
    • 1
  • Won Kil Pae
    • 1
  1. 1.Department of SurgeryKangbuk Samsung Hospital, Sungkyunkwan University School of MedicineJongro-kuKorea

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