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World Journal of Surgery

, Volume 30, Issue 1, pp 91–99 | Cite as

Clinical Significance of Metastasis to the Central Compartment from Papillary Microcarcinoma of the Thyroid

  • Yasuhiro ItoEmail author
  • Chisato Tomoda
  • Takashi Uruno
  • Yuuki Takamura
  • Akihiro Miya
  • Kaoru Kobayashi
  • Fumio Matsuzuka
  • Kanji Kuma
  • Akira Miyauchi
Article

Abstract

We previously demonstrated that for papillary microcarcinoma (PMC), (1) patients with lateral lymph node metastasis detected on preoperative ultrasonography (US) are more likely to develop recurrence, and (2) dissection of the lateral compartment does not improve the prognosis of patients without US-detectable lateral metastasis. In this study, we focused on metastasis from PMC to the central compartment. We investigated the clinical significance of lymph nodes in the central compartment using the same series of 600 patients as used in the previous study. Ultrasound-diagnosed central node metastasis could be found in 30 patients (20.0%). Although the specificity of US for detecting central node metastasis was 99.1%, sensitivity was only 10.9%. Neither US-diagnosed nor pathologically confirmed central node metastasis affected the disease-free survival (DFS) rate of PMC patients. Furthermore, in cases where PMC was located only in one lobe, central node dissection in the contralateral lobe did not improve the DFS rate. These findings suggest that, for PMC, (1) US is an insensitive technique for detecting the central node metastasis, (2) the presence of central node metastasis is unrelated to DFS of patients, and (3) when performing lobectomy for PMC involving only one lobe, dissection of the central compartment in the contralateral lobe is optional.

Keywords

Recurrent Laryngeal Nerve Papillary Carcinoma Central Compartment Lateral Compartment Remnant Thyroid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Société Internationale de Chirurgie 2005

Authors and Affiliations

  • Yasuhiro Ito
    • 1
    Email author
  • Chisato Tomoda
    • 1
  • Takashi Uruno
    • 1
  • Yuuki Takamura
    • 1
  • Akihiro Miya
    • 1
  • Kaoru Kobayashi
    • 1
  • Fumio Matsuzuka
    • 1
  • Kanji Kuma
    • 1
  • Akira Miyauchi
    • 1
  1. 1.Department of SurgeryKuma HospitalKobe CityJapan

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