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World Journal of Surgery

, Volume 28, Issue 11, pp 1110–1114 | Cite as

Preoperative Neck Ultrasonographic Mapping for Persistent/Recurrent Papillary Thyroid Cancer

  • Hussam M. BinYousef
  • Ali S. AlzahraniEmail author
  • Saif S. Al-Sobhi
  • Hamed S. Al Suhaibani
  • Mohammed A. Chaudhari
  • Hussain M. Raef
Article

Abstract

Surgical resection of persistent/recurrent (P/R) papillary thyroid cancer (PTC), when localized to the neck, is generally recommended; however, its impact on the course of the disease is not clear. We introduced a new technique in the form of preoperative neck ultrasonographic mapping (US-M) to improve the outcome of the surgical resection of P/R PTC. A total of 19 patients had undergone regional (central, lateral, or both) neck dissection before introducing the current technique (group 1, or G1), and 26 patients (group 2, or G2) had limited lymph node resection guided by US-M with findings accurately plotted on a standard diagram. All of the operations were performed by a single surgeon. The surgical outcomes of the two groups were compared. The resected lesions were positive for PTC in 17 patients (89.5%) in G1 and in 25 patients (96.2%) in G2. In G2, the intraoperative findings exactly matched the US-M in 23 patients (88.5%). Postoperatively, neck US became negative in 50% in G1 and in 83.3% in G2 (p = 0.02). Thyroglobulin (Tg) became undetectable in 37.5% in G1 and 52.3% in G2 (p = 0.37). Whole-body iodine scans (WBS) became negative in one of six patients (16.7%) in G1, and in three of four patients (75%) in G2, (p = 0.06). After a mean follow-up of 23.8 ± 7.1 months in G1 and 9.8 ± 4.7 months in G2, 6 patients (31.6%) in G1 and 15 patients (62.5%) in G2 were in remission (p = 0.04), whereas the disease persisted in 13 cases (68.4%) in G1 and 9 (37.5%) in G2 (p = 0.04). In conclusion, US-M improved the surgical outcome, as evidenced by the postoperative US, Tg, and WBS findings and the higher remission rate for the G2 patients than for the G1 patients.

Keywords

Neck Dissection Papillary Thyroid Cancer Whole Body Scan 131I Therapy Modify Neck Dissection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Société Internationale de Chirurgie 2004

Authors and Affiliations

  • Hussam M. BinYousef
    • 1
  • Ali S. Alzahrani
    • 2
    Email author
  • Saif S. Al-Sobhi
    • 1
  • Hamed S. Al Suhaibani
    • 3
  • Mohammed A. Chaudhari
    • 4
  • Hussain M. Raef
    • 2
  1. 1.Department of SurgeryKing Faisal Specialist Hospital & Research CentreRiyadhSaudi Arabia
  2. 2.Department of MedicineKing Faisal Specialist Hospital & Research CentreRiyadhSaudi Arabia
  3. 3.Department of RadiologyKing Faisal Specialist Hospital & Research CentreRiyadhSaudi Arabia
  4. 4.Epidemiology, Biostatistics, and Scientific ComputingKing Faisal Specialist Hospital & Research CentreRiyadhSaudi Arabia

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