Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL): An Open Wound

  • Eduardo de Faria Castro FleuryEmail author
Letter to the Editor


Since 2017, there have been an increasing number of reported cases regarding breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) in the literature. Although significant attention was dispensed for this relevant issue, there is no consensus on what the trigger points for disease development are. BIA-ALCL trigger point speculation includes textured breast implants, bacterial contamination, and genetic factors. However, little attention is given by the literature regarding gel bleeding and the toxicity of polydimethylsiloxane. This opinion-based article aims to report our experience in a prospective study of breast implants and share our knowledge regarding silicone-induced granuloma of breast implant capsule.

Level of Evidence V

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The author acknowledges Dr. Gabriel Salum D’Alessandro, who made the capsulectomy and the implant explantation.


There is no funding support.

Compliance with Ethical Standards

Conflict of interest

There is no competing interest.

Ethics Approval

Waived due to the type of manuscript.

Informed Consent

Informed consent was obtained from the patient.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and International Society of Aesthetic Plastic Surgery 2020

Authors and Affiliations

  1. 1.Faculdade de MedicinaUniversidade São CamiloSão PauloBrazil
  2. 2.Instituto Brasileiro de Controle do Câncer – IBCCSão PauloBrazil

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