Aesthetic Plastic Surgery

, Volume 42, Issue 6, pp 1492–1498 | Cite as

Breast Implant-Associated Anaplastic Large Cell Lymphoma: Immediate or Delayed Implant Replacement?

  • Julien J. Shine
  • Elie Boghossian
  • Gabriel Beauchemin
  • Vasilios W. Papanastasiou
  • Daniel E. BorsukEmail author
Original Article Breast Surgery



Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare and recently described type of peripheral T-cell lymphoma. Fewer than 550 cases have been reported worldwide. Although BIA-ALCL is usually indolent, early diagnosis and treatment have been shown to improve outcome.

Case Description

This case report describes the management of a 50-year-old healthy Caucasian woman presenting with rapid painful enlargement of the left breast. Imaging revealed findings consistent with BIA-ALCL. This diagnosis was confirmed by fine needle aspiration cytology and subsequent pathological analysis. Bilateral removal of implants, complete left capsulectomy and immediate bilateral implant exchange were performed.


No consensus currently exists regarding optimal time of implant exchange and management of the contralateral capsule. The immediate replacement with smooth implants was thoroughly discussed with the patient and endorsed by expert opinion, given complete removal of the disease. There was no sign of recurrence at 6 months. Close clinical and radiological visits are planned for the next years.

Level of Evidence V

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors


BIA-ALCL Anaplastic large cell lymphoma Breast implant lymphoma Case report Total capsulectomy Immediate implant replacement 



The authors would like to thank Dr. Mark W. Clemens of the MD Anderson Cancer Center for his valued advice regarding BIA-ALCL and contribution to this report. The authors would also like to acknowledge Dr. Tony Petrella for his generous contribution in the histopathological analysis of this case.

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.

Human and Animal Rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

Informed Consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature and International Society of Aesthetic Plastic Surgery 2018

Authors and Affiliations

  • Julien J. Shine
    • 1
  • Elie Boghossian
    • 1
  • Gabriel Beauchemin
    • 1
  • Vasilios W. Papanastasiou
    • 2
  • Daniel E. Borsuk
    • 1
    • 3
    Email author
  1. 1.Department of Plastic and Reconstructive Surgery, Hôpital Maisonneuve-RosemontUniversité de MontréalMontrealCanada
  2. 2.Department of Plastic and Reconstructive SurgeryMcGill University Health CenterMontrealCanada
  3. 3.Hôpital Sainte-JustineMontrealCanada

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