Aesthetic Plastic Surgery

, Volume 37, Issue 6, pp 1176–1181 | Cite as

Improved Scar Appearance With Combined Use of Silicone Gel and Vitamin C for Asian Patients: A Comparative Case Series

  • In Sik Yun
  • Han-Su Yoo
  • Yong Oock KimEmail author
  • Dong Kyun Rah
Original Article Non-Surgical Aesthetic



In Asians, facial scars, even fine surgical scars, often can be conspicuous and uncomfortable. The authors used a topical silicone gel containing vitamin C on facial scars for the purpose of making the scar less distinct.


The study enrolled 80 patients. For the experimental group, the topical silicone gel mixture containing vitamin C was applied from the time of stitch removal to 6 months after the operation. The control group did not undergo any adjunctive treatment. Each participant was evaluated using the modified Vancouver Scar Scale (VSS) as well as erythema and melanin indices by spectrophotometer.


With the modified VSS, the experimental group showed a significant decrease in scar elevation (p = 0.026) and erythema (p = 0.025). The hypo- or hyperpigmentation of the scars was more normalized in the experimental group. In the measured results via spectrophotometer, the experimental group showed a significant decrease in the melanin index (p = 0.045). The erythema index showed a statistically significant difference between the time of stitch removal and 6 months after the operation in the experiment group only.


Topical use of silicone gel containing vitamin C has the effect of improving the appearance of fine surgical scars in Asian facial skin.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors


Asian Surgical scar Topical silicone gel Vitamin C 


Conflict of interest

The authors declare that they have no conflict of interest.


  1. 1.
    Chernoff WG, Cramer H, Huang SS (2007) The efficacy of topical silicone gel elastomers in the treatment of hypertrophic scars, keloid scars, and postlaser exfoliation erythema. Aesthet Plast Surg 31:495–500CrossRefGoogle Scholar
  2. 2.
    Sproat JE, Dalcin A, Weitauer N et al (1992) Hypertrophic sternal scars: silicone gel sheet versus Kenalog injection treatment. Plast Reconstr Surg 90:988–992PubMedCrossRefGoogle Scholar
  3. 3.
    Chan KY, Lau CL, Adeeb SM et al (2005) A randomized, placebo-controlled, double-blind, prospective clinical trial of silicone gel in prevention of hypertrophic scar development in median sternotomy wound. Plast Reconstr Surg 116:1013–1020PubMedCrossRefGoogle Scholar
  4. 4.
    Perkins K, Davey RB, Wallis KA (1983) Silicone gel: a new treatment for burn scars and contractures. Burns 9:201–204CrossRefGoogle Scholar
  5. 5.
    van der Wal MB, van Zuijlen P, van de Ven P et al (2010) Topical silicone gel versus placebo in promoting the maturation of burn scars: a randomized controlled trial. Plast Reconstr Surg 126:524–531PubMedCrossRefGoogle Scholar
  6. 6.
    Sakuraba M, Takahashi N, Akahoshi T et al (2011) Use of silicone gel sheets for prevention of keloid scars after median sternotomy. Surg Today 41:496–499PubMedCrossRefGoogle Scholar
  7. 7.
    Lee SM, Ngim CK, Chan YY et al (1996) A comparison of Sil-K and epiderm in scar management. Burns 22:483–487PubMedCrossRefGoogle Scholar
  8. 8.
    Nikkonen MM, Pitkanen JM, Al Qattan MM (2001) Problems associated with the use of silicone gel sheeting for hypertrophic scars in the hot climate of Saudi Arabia. Burns 27:498–501PubMedCrossRefGoogle Scholar
  9. 9.
    Vaxman F, Olender S, Lambert A et al (1996) Can the wound-healing process be improved by vitamin supplementation? Experimental study on humans. Eur Surg Res 28:306–314PubMedCrossRefGoogle Scholar
  10. 10.
    Cabbabe EB, Korock SW (1986) Wound healing in vitamin C-deficient and nondeficient guinea pigs: a pilot study. Ann Plast Surg 17:330–334PubMedCrossRefGoogle Scholar
  11. 11.
    Emamghorashi F, Owji SM, Motamedifar M (2011) Evaluation of effectiveness of vitamins C and E on prevention of renal scar due to pyelonephritis in rat. Adv Urol 2011:489–496CrossRefGoogle Scholar
  12. 12.
    Yun IS, Lee WJ, Rah DK et al (2010) Skin color analysis using a spectrophotometer in Asians. Skin Res Technol 16:311–315PubMedGoogle Scholar
  13. 13.
    Rhee S, Koh S, Lee D et al (2010) Aesthetic effect of silicone gel on surgical scars in Asians. J Craniofac Surg 21:706–710PubMedCrossRefGoogle Scholar
  14. 14.
    Spencer JM (2010) Case series: evaluation of a liquid silicone gel on scar appearance following excisional surgery: a pilot study. J Drugs Dermatol 9:856–858PubMedGoogle Scholar
  15. 15.
    Pladellorens J, Pintó A, Segura J et al (2008) A device for the color measurement and detection of spots on the skin. Skin Res Technol 14:65–70PubMedGoogle Scholar
  16. 16.
    Pershing LK, Tirumala VP, Nelson JL et al (2008) Reflectance spectrophotometer: the dermatologists’ sphygmomanometer for skin phototyping? J Invest Dermatol 128:1633–1640PubMedCrossRefGoogle Scholar
  17. 17.
    Kim YS, Lew DH, Tark KC et al (2010) Effect of recombinant human epidermal growth factor against cutaneous scar formation in murine full-thickness wound healing. J Korean Med Sci 25:589–596PubMedCrossRefGoogle Scholar
  18. 18.
    Khatri KA, Mahoney DL, McCartney MJ (2011) Laser scar revision: a review. J Cosmet Laser Ther 13:54–62PubMedCrossRefGoogle Scholar
  19. 19.
    Aust MC, Knobloch K, Reimers K et al (2010) Percutaneous collagen induction therapy: an alternative treatment for burn scars. Burns 36:836–843PubMedCrossRefGoogle Scholar
  20. 20.
    Kim E, Chang T, Hong J et al (2011) Use of tattooing to camouflage various scars. Aesthet Plast Surg 38:1–4Google Scholar
  21. 21.
    Kim SW, Han HH, Seo JW et al (2012) Two cases of lower body contouring with a spiral and vertical medial thigh lift. Arch Plast Surg 39:67–70PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York and International Society of Aesthetic Plastic Surgery 2013

Authors and Affiliations

  • In Sik Yun
    • 1
  • Han-Su Yoo
    • 1
  • Yong Oock Kim
    • 1
    Email author
  • Dong Kyun Rah
    • 1
  1. 1.Department of Plastic & Reconstructive Surgery, Institute for Human Tissue RestorationYonsei University College of MedicineSeoulKorea

Personalised recommendations