A Prospective, Noninterventional Study of the Treatment of the Aging Hand with Juvéderm Ultra® 3 and Juvéderm® Hydrate
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Hand rejuvenation aims to restore volume and produce smooth, elastic skin. A combined treatment has been proposed: Juvéderm Ultra® 3 for filling and smoothing the skin and Juvéderm® Hydrate to rehydrate and restore skin quality.
Twenty physicians enrolled 99 subjects (i.e., 198 hands). At the first visit, hands were injected with Juvéderm Ultra® 3. At the second visit (day 15) hands were treated with Juvéderm® Hydrate. A final assessment was made at day 30.
Ninety-eight percent of subjects were female (mean age = 60.3 years). Mean volumes injected were 1.02 ml Juvéderm Ultra® 3 per hand at day 0 and 0.91 ml Juvéderm® Hydrate per hand at day 15. Mean grading on the Hand Aging Scale was 3.18 preinjection, which decreased to 1.73 on study completion (p < 0.0001). Injections were rated as “very easy/easy” in 99.4 and 98.9 % of cases for Juvéderm Ultra® 3 and Juvéderm® Hydrate, respectively. Most physicians found both products “very easy/easy” to massage. Physician evaluation based on the Global Aesthetic Improvement Scale (GAIS) showed that the proportion of “very much/much improved” was significantly higher at days 15 and 30 compared to baseline (63.7 and 70.3 vs. 41.8 %). Patient GAIS scores showed that the proportion of “much improved” was significantly higher at day 30 than at day 15 (53.1 vs. 43.9 %). Over 94 % of physicians and approximately 90 % of subjects would recommend treatment. The adverse event rate was 8.2 %, including edema, hematoma, redness, and pain.
Combined Juvéderm Ultra® 3 and Juvéderm® Hydrate treatment is effective and safe for rejuvenating the aging hand.
Level of Evidence III
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KeywordsAging hand Hand rejuvenation Juvéderm® Hydrate Juvéderm Ultra® 3
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