Aesthetic Plastic Surgery

, Volume 36, Issue 4, pp 949–954 | Cite as

A Prospective, Noninterventional Study of the Treatment of the Aging Hand with Juvéderm Ultra® 3 and Juvéderm® Hydrate

Original Article

Abstract

Background

Hand rejuvenation aims to restore volume and produce smooth, elastic skin. A combined treatment has been proposed: Juvéderm Ultra® 3 for filling and smoothing the skin and Juvéderm® Hydrate to rehydrate and restore skin quality.

Methods

Twenty physicians enrolled 99 subjects (i.e., 198 hands). At the first visit, hands were injected with Juvéderm Ultra® 3. At the second visit (day 15) hands were treated with Juvéderm® Hydrate. A final assessment was made at day 30.

Results

Ninety-eight percent of subjects were female (mean age = 60.3 years). Mean volumes injected were 1.02 ml Juvéderm Ultra® 3 per hand at day 0 and 0.91 ml Juvéderm® Hydrate per hand at day 15. Mean grading on the Hand Aging Scale was 3.18 preinjection, which decreased to 1.73 on study completion (p < 0.0001). Injections were rated as “very easy/easy” in 99.4 and 98.9 % of cases for Juvéderm Ultra® 3 and Juvéderm® Hydrate, respectively. Most physicians found both products “very easy/easy” to massage. Physician evaluation based on the Global Aesthetic Improvement Scale (GAIS) showed that the proportion of “very much/much improved” was significantly higher at days 15 and 30 compared to baseline (63.7 and 70.3 vs. 41.8 %). Patient GAIS scores showed that the proportion of “much improved” was significantly higher at day 30 than at day 15 (53.1 vs. 43.9 %). Over 94 % of physicians and approximately 90 % of subjects would recommend treatment. The adverse event rate was 8.2 %, including edema, hematoma, redness, and pain.

Conclusion

Combined Juvéderm Ultra® 3 and Juvéderm® Hydrate treatment is effective and safe for rejuvenating the aging hand.

Level of Evidence III

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors at www.springer.com/00266.

Keywords

Aging hand Hand rejuvenation Juvéderm® Hydrate Juvéderm Ultra®

References

  1. 1.
    Abrams HL, Lauber JS (1990) Hand rejuvenation. The state of the art. Dermatol Clin 8(3):553–561PubMedGoogle Scholar
  2. 2.
    Shamban AT (2009) Combination hand rejuvenation procedures. Aesthet Surg J 29(5):409–413PubMedCrossRefGoogle Scholar
  3. 3.
    Carruthers A, Carruthers J, Hardas B, Kaur M, Goertelmeyer R, Jones D, Rzany B, Cohen J, Kerscher M, Flynn TC, Maas C, Sattler G, Gebauer A, Pooth R, McClure K, Simone-Korbel U, Buchner L (2008) A validated hand grading scale. Dermatol Surg 34(Suppl 2):S179–S183PubMedCrossRefGoogle Scholar
  4. 4.
    Levy PM, De Boulle K, Raspaldo H (2008) Comparison of injection comfort and ease with Juvéderm ULTRA 3 and Surgiderm 30 XP. Poster presented at International Master Course on Aging Skin (IMCAS), Paris, France, 9–12 January 2008Google Scholar
  5. 5.
    Smith KC, Melnychuk M (2005) Five percent lidocaine cream applied simultaneously to the skin and mucosa of the lips creates excellent anesthesia for filler injections. Dermatol Surg 31:1635–1637PubMedCrossRefGoogle Scholar
  6. 6.
    Shamma AR, Guy RJ (2007) Laser ablation of unwanted hand veins. Plast Reconstr Surg 120(7):2017–2024PubMedCrossRefGoogle Scholar
  7. 7.
    Jakubietz R, Grünert JG, Kloss DF, Meffert R, Schmidt K, Jakubietz MG (2009) Aging and the appearance of the hand. Hautarzt 60(3):217, 220-225Google Scholar

Copyright information

© Springer Science+Business Media, LLC and International Society of Aesthetic Plastic Surgery 2012

Authors and Affiliations

  1. 1.Centre Laser Dermatologique Laser MDStrasbourgFrance

Personalised recommendations