Aesthetic Plastic Surgery

, Volume 37, Issue 1, pp 194–197 | Cite as

Massive Subcutaneous Emphysema After Carbon Dioxide Mesotherapy

  • Wenceslao M. CalongeEmail author
  • Drahoslava Lesbros-Pantoflickova
  • Marina Hodina
  • Badwi Elias
Letter to the Editor Non-Surgical Aesthetic


The authors report the observation of a 43-year-old woman with severe pain on her right upper abdominal quadrant. Differential diagnoses included acute cholecystitis, spontaneous pneumothorax, perforated appendicitis and a recidive of renal calculus. CT-scan showed a huge subdermal gas bubble along her right flank and anterior abdominal wall up to the submammary fold. Only at this point, the patient admitted to have undergone a carboxytherapy procedure on both thighs one day before onset of pain in a paramedical facility. As some of the injection trajects were still patent on CT-scan, she received prophylactic antibiotic coverage. Though there was a complete resorption of gas after 10 days, dysesthesias and muscle contracture persisted for 3 weeks. To the authors’ knowledge this migration and coalescence of injected gas in a single bubble has not been previously reported.

Level of Evidence V

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors


Iatrogeny Complications Mesotherapy Carboxytherapy Subcutaneous emphysema 


Conflict of interest

The authors have no conflicts of interest to disclose.


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Copyright information

© Springer Science+Business Media New York and International Society of Aesthetic Plastic Surgery 2013

Authors and Affiliations

  • Wenceslao M. Calonge
    • 1
    Email author
  • Drahoslava Lesbros-Pantoflickova
    • 1
  • Marina Hodina
    • 2
  • Badwi Elias
    • 3
  1. 1.Department of MedicineClinique de GenolierGenolierSwitzerland
  2. 2.Department of RadiologyClinique de GenolierGenolierSwitzerland
  3. 3.Department of Plastic, Reconstructive and Aesthetic SurgeryClinique de GenolierGenolierSwitzerland

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